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TPI-287

Known as: TPI 287, Taxane Analogue TPI 287 
A synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in… 
National Institutes of Health

Related topics

Related topics

3 relations
Microtubule ProcessNCIt Antineoplastic Agent Terminology

Broader (1)

Taxoids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Prognostic scores for evaluating the survival benefit of regorafenib or trifluridine/tipiracil in patients with metastatic colorectal cancer: an exploratory analysis of the REGOTAS study
Background Although regorafenib or trifluridine/tipiracil (FTD/TPI) has been recognized as a later-line standard treatment in… 
2018
2018
Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells
Salvage chemotherapy for refractory metastatic colorectal cancer using trifluridine/tipiracil (FTD/TPI) and regorafenib has shown… 
2017
2017
Compassionate use program with FDT-TPI (trifluridine-tipiracil) in pre-treated metastatic colorectal cancer patients: Spanish real world data.
e15019Background: Trifluridine/tipiracil (FTD-TPI) is comprised of an antineoplastic nucleoside analog, trifluridine, and a… 
2016
2016
A phase I study of TPI 287 in combination with temozolomide for patients with metastatic melanoma
TPI 287 is a synthetic taxane derivative with structural modifications allowing for central nervous system penetration and… 
2012
2012
Influence of Winding Structure and the Effect of MMF Harmonics to the Spindle Motor Performance for Ultrahigh TPI HDD
The technologies for maintaining high recording density to suppress mechanical vibration and media flutter for ultrahigh TPI hard… 
2011
2011
PERFOMANCE OF 2 MeV , 2 kA , 200 ns LINEAR INDUCTION ACCELERATOR WITH ULTRA LOW BEAM EMITTANCE FOR X-RAY FLASH RADIOGRAPHY
LIA-2 linear induction accelerator is designed in Budker INP as an injector for full scale 20 MeV linear induction accelerator… 
2008
2008
Life-cycle performance of structures: combining expert judgment and results of inspection
Current bridge management systems base decisions on the results of visual inspections. These systems consider visual inspection… 
2005
2005
The type I/type II cytochrome c3 complex: an electron transfer link in the hydrogen-sulfate reduction pathway.
1994
1994
KONYA YÖRESİ İLKOKUL ÇOCUKLARINDA “TREATMENT PRIORITY INDEX” (TPI) UYGULAMASI (EPİDEMİYOLOJİK ÇALIŞMA)*
OZET: Bu calisma Konya yoresi ilkokui cocuklarinin ortodontik tedavi gereksinimlerini belirlemek amaciyla planlanmistir… 
1990
1990
Stratified, weak stratified and three-valued semantics
We investigate the relationship between three-valued Kripke/Kleene semantics and stratified semantics for stratifiable logic… 
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