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TORC1 signaling

Known as: TORC1 signal transduction 
A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated… 
National Institutes of Health

Related topics

Related topics

2 relations
negative regulation of TORC1 signaling

Narrower (1)

negative regulation of macroautophagy by TORC1 signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Ecm33 is a novel factor involved in efficient glucose uptake for nutrition‐responsive TORC1 signaling in yeast
Glucose uptake is crucial for providing both an energy source and a signal that regulates cell proliferation. Therefore, it is… 
2016
2016
Histone H3 and TORC1 prevent organelle dysfunction and cell death by promoting nuclear retention of HMGB proteins
How cells respond and adapt to environmental changes, such as nutrient flux, remains poorly understood. Evolutionarily conserved… 
Review
2016
Review
2016
Views eIF 4 A moonlights as an off switch for TORC 1
T arget of rapamycin complex 1 (TORC1) is an evolutionarily conserved regulator of cell growth and metabolism. It integrates… 
2015
2015
Tryptophan-Dependent Control of Colony Formation After DNA Damage via Sea3-Regulated TORC1 Signaling in Saccharomyces cerevisiae
The Saccharomyces cerevisiae Iml1 complex inhibits TORC1 signaling and SEACAT antagonizes the Iml1 complex. Conditions in which… 
2015
2015
Abstract 477: Inhibition of MEK confers hypersensitivity to X-radiation in the context of BRAF mutation in a model of childhood astrocytoma
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA Patients with recurrent low-grade brain tumors… 
2014
2014
Crosstalk between the Tor and Gcn2 pathways in response to different stresses
Regulating growth and the cell cycle in response to environmental fluctuations is important for all organisms in order to… 
2013
2013
Regulation of nuclear tRNA export in response to nutrient stress is not evolutionarily conserved and requires the TORC1 and PKA signaling pathways in Saccharomyces cerevisiae
REGULATION OF NUCLEAR tRNA EXPORT IN RESPONSE TO NUTRIENT STRESS IS NOT EVOLUTIONARILY CONSERVED AND REQUIRES THE TORC1 AND PKA… 
2011
2011
S3-4: ER Downregulation with Fulvestrant in Combination with pan-PI3K Inhibitor BKM120 Synergizes Against ER+/PI3K-Mutant Breast Cancer Xenografts In Vivo.
ER+ breast cancers typically respond to aromatase inhibitors (AIs), but a significant fraction exhibit de novo or acquired… 
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