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TOR complex

Known as: TOR signaling complex location, TOR complex location, TOR signaling complex 
A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and… Expand
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Cell metabolism and growth are matched to nutrient availability via the amino-acid-regulated mechanistic target of rapamycin… Expand
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Highly Cited
2015
Highly Cited
2015
YAP (yes-associated protein) and TAZ are oncogenic transcriptional co-activators downstream of the Hippo tumor-suppressor pathway… Expand
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Review
2014
Review
2014
The mechanistic target of rapamycin complex I (mTORC1) is a central regulator of cellular and organismal growth, and… Expand
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Highly Cited
2014
Highly Cited
2014
The mechanistic target of rapamycin complex 1 (mTORC1) kinase is a major regulator of cell growth that responds to numerous… Expand
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Highly Cited
2014
Highly Cited
2014
SQSTM1/p62 (sequestosome 1) is a multifunctional signaling molecule, involved in a variety of cellular pathways. SQSTM1 is one of… Expand
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Highly Cited
2014
Highly Cited
2014
The mechanistic target of rapamycin complex 1 (mTORC1) kinase is a sensor of different environmental conditions and regulator of… Expand
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Highly Cited
2013
Highly Cited
2013
The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates organismal growth in response to many environmental cues… Expand
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Highly Cited
2012
Highly Cited
2012
The nuclear translocation of a transcription factor that promotes lysosomal biogenesis is inhibited when lysosomal function is… Expand
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Highly Cited
2012
Highly Cited
2012
Dissecting Rapamycin Responses Long-term treatment of mice and other organisms with the drug rapamycin extends life span. But, at… Expand
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Highly Cited
2010
Highly Cited
2010
Mammalian target of rapamycin (mTOR) is a member of the phosphatidylinositol 3-kinase-related kinase (PIKK) family and is a major… Expand
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