TOR complex

Known as: TOR signaling complex location, TOR complex location, TOR signaling complex 
A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
05101519932017

Papers overview

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2015
2015
YAP (yes-associated protein) and TAZ are oncogenic transcriptional co-activators downstream of the Hippo tumor-suppressor pathway… (More)
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2015
2015
The mechanistic target of rapamycin complex 2 (mTORC2) regulates cell survival and cytoskeletal organization by phosphorylating… (More)
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Highly Cited
2014
Highly Cited
2014
The mechanistic target of rapamycin complex 1 (mTORC1) kinase is a sensor of different environmental conditions and regulator of… (More)
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Highly Cited
2013
Highly Cited
2013
In chronic kidney disease (CKD), loss of functional nephrons results in metabolic and mechanical stress in the remaining ones… (More)
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2013
2013
Epithelial-to-mesenchymal transition (EMT) causes fibrosis, cancer progression and metastasis. Integrin-linked kinase (ILK) is a… (More)
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2011
2011
Mammalian target of rapamycin complex (mTORC) regulates a variety of cellular responses including proliferation, growth… (More)
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2011
2011
Accumulating evidence indicates that dysfunction of mitochondria is a common feature of Parkinson disease. Functional loss of a… (More)
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Highly Cited
2010
Highly Cited
2010
Aberrant activation of the mammalian target of rapamycin complex 1 (mTORC1) is a common molecular event in a variety of… (More)
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2010
2010
Although preclinical work with rapalogs suggests potential in treatment of multiple myeloma (MM), they have been less successful… (More)
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Highly Cited
2008
Highly Cited
2008
Protein kinase C (PKC) is involved in a wide array of cellular processes such as cell proliferation, differentiation and… (More)
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