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TOR complex

Known as: TOR signaling complex location, TOR complex location, TOR signaling complex 
A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Methionine abrogates the renoprotective effect of a low-protein diet against diabetic kidney disease in obese rats with type 2 diabetes
Dietary interventions, including a low-protein diet (LPD) and methionine (Met) restriction, have shown longevity, anti-aging and… 
2018
2018
Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation.
Background Feeding stimulates protein synthesis in skeletal muscle of neonates and this response is regulated through activation… 
2017
2017
mTORC1 suppresses PIM3 expression via miR-33 encoded by the SREBP loci
The mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth that is often aberrantly activated… 
2015
2015
The Endosomal Sorting Complex Required for Transport Pathway Mediates Chemokine Receptor CXCR4-promoted Lysosomal Degradation of the Mammalian Target of Rapamycin Antagonist DEPTOR*
Background: Akt signaling is activated by G protein-coupled receptors (GPCRs) via the PI3K-mTORC2 signaling cascade, but… 
2014
2014
Mutant Ras Elevates Dependence on Serum Lipids and Creates a Synthetic Lethality for Rapamycin
The conversion of normal cells to cancer cells involves a shift from catabolic to anabolic metabolism involving increased glucose… 
2014
2014
Mammalian Target of Rapamycin Complex 2 Modulates αβTCR Processing and Surface Expression during Thymocyte Development
An efficient immune response relies on the presence of T cells expressing a functional TCR. Whereas the mechanisms generating TCR… 
2014
2014
Ras transformation uncouples the kinesin-coordinated cellular nutrient response
Significance The kinesin family member 2C (KIF2C) that regulates microtubule depolymerization, is up-regulated in a number of… 
2012
2012
Integrity of mTORC2 is dependent on the rictor Gly-934 site
Growth factor signaling coupled to activation of the phosphatidylinositol-3-OH kinase (PI3K)/Akt pathway plays a crucial role in… 
2012
2012
Mechanistic Target of Rapamycin Complex 1 (mTORC1)-mediated Phosphorylation Is Governed by Competition between Substrates for Interaction with Raptor*
Background: mTORC1 targets p70S6K1 and 4E-BP1 are phosphorylated in response to nutrient and hormonal signals. Results: Loss of… 
2011
2011
Protection of porcine endothelial cells against apoptosis with interleukin‐4
Black SM, Benson BA, Idossa D, Vercellotti GM, Dalmasso AP. Protection of porcine endothelial cells against apoptosis with… 
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