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TOP2B protein, human

Known as: EC 5.99.1.3, topoisomerase (DNA) II beta 180kDa protein, human, TOP2B 
DNA topoisomerase 2-beta (1626 aa, ~183 kDa) is encoded by the human TOP2B gene. This protein plays a role in DNA relaxation.
National Institutes of Health

Related topics

Related topics

13 relations
5-chloroquinoxaline-2-sulfanilamideATPase DomainCell NucleusChromosome Condensation

Broader (1)

DNA topoisomerase II beta

Papers overview

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2018
2018
Role of TOP2B in photoreceptor gene regulatory network by single-cell transcriptome analysis
OF THE THESIS ROLE OF Top2b IN PHOTORECEPTOR GENE REGULATORY NETWORK BY SINGLE-CELL TRANSCRIPTOME ANALYSIS By ALEXANDRIA PINTO… 
2018
2018
Copper-Catalyzed Synthesis, Bio-Evaluation, and in Silico Studies of 2-Aryl-N-alkylbenzimidazoles as Neuroprotective Agents
2-aryl-N-alkylbenzimidazole derivatives synthesized by CuI/PPh3 promoted direct coupling of N-alkylbenzimidazoles with aryl… 
2017
2017
Chromosome Loop Anchors Are Susceptible to DNA Double-Strand Breaks.
TOP2B induces double-strand breaks at CTCF-bound DNA loop anchors, increasing genomic rearrangements. 
2017
2017
The Telomeric Noncoding RNA TERRA Regulates Telomere Stability.
TERRA activates the DNA damage response at short telomeres to prevent premature senescence. 
2014
2014
Relation of ETS transcription factor family member ERG, androgen receptor and topoisomerase 2β expression to TMPRSS2-ERG fusion status in prostate cancer.
Fusion of TMPRSS2 with ERG in prostate cells is determined by double-strand DNA breaks induced by androgen signaling and… 
2010
2010
Prostate cancer: gene fusions
volume 7 | sePtemBer 2010 | 473 research highlights two studies, published in Nature Genetics and Nature Medicine, have shed…