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TOFACITINIB CITRATE

Known as: 1-Piperidinepropanenitrile, 4-Methyl-3-(Methyl-7H-Pyrrolo(2,3-d)Pyrimidin-4-ylamino)-Beta-Oxo-, (3R,4R)-, 2-Hydroxy-1,2,3-Propanetricarboxylate (1:1) 
National Institutes of Health

Papers overview

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2016
2016
Pfizer's Xeljanz (tofacitinib citrate) was the first Janus kinase (JAK) inhibitor to reach the market for rheumatoid arthritis… 
2016
2016
The invention belongs to the field of medicine and chemical engineering and particularly relates to a preparation method of… 
2016
2016
The invention discloses Tofacitinib citrate tablets composed of Tofacitinib citrate and pharmaceutically acceptable auxiliary… 
2015
2015
建立了高效液相色谱法同时测定枸橼酸托法替布中的4种光学异构体.采用Chiralpak IC色谱柱,以甲基叔丁醚∶乙醇∶二乙胺(70∶30∶0.1)为流动相,检测波长为280 nm.4种光学异构体之间的分离度均大于2.0,线性范围为0.1~120 μg/ml… 
2015
2015
The invention belongs to the field of medicine synthesis and particularly relates to a Tofacitinib citrate synthesizing method… 
2014
2014
The invention relates to a method for preparing tofacitinib citrate. The method comprises the following steps: by taking N-methyl… 
Review
2014
Review
2014
Tofacitinib citrate,an inhibitor of Janus kinases(JAKs),is indicated for the treatment of adult patients with moderately to… 
2014
2014
The invention discloses a content determining and related substance detection method for tofacitinib citrate. The method is…