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TNT003

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2014-2018
01220142018

Related topics

Related topics

1 relation

Broader (1)

Monoclonal Antibodies

Related mentions per year

Related mentions per year

1950-2018
1960198020002020
TNT003
Monoclonal Antibodies

Papers overview

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2018
2018
The Anti-C1s Antibody TNT003 Prevents Complement Activation in the Skin Induced by Bullous Pemphigoid Autoantibodies.
 
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2017
2017
Complement-Mediated Enhancement of Monocyte Adhesion to Endothelial Cells by HLA Antibodies, and Blockade by a Specific Inhibitor of the Classical Complement Cascade, TNT003
BACKGROUND Antibody-mediated rejection (AMR) of most solid organs is characterized by evidence of complement activation and/or… (More)
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2017
2017
Effect of the Anti‐C1s Humanized Antibody TNT009 and Its Parental Mouse Variant TNT003 on HLA Antibody–Induced Complement Activation—A Preclinical In Vitro Study
The classic pathway (CP) of complement is believed to significantly contribute to alloantibody-mediated transplant injury, and… (More)
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2016
2016
Uncoupling complement C1s activation from C1q binding in apoptotic cell phagocytosis and immunosuppressive capacity.
Complement activation contributes to inflammation in many diseases, yet it also supports physiologic apoptotic cells (AC… (More)
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2015
2015
An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA.
Antibody-mediated rejection (AMR) of solid organ transplants (SOT) is characterized by damage triggered by donor-specific… (More)
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2014
2014
TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins.
Activation of the classical pathway (CP) of complement is often associated with autoimmune disorders in which disease pathology… (More)
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2014
2014
Complement, cold agglutinins, and therapy.
In this issue of Blood, Shi and coworkers show that TNT003, a mouse monoclonal antibody targeting complement protein C1s… (More)
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