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TNRC6A gene

Known as: CAGH26, trinucleotide repeat containing 6A, KIAA1460 
National Institutes of Health

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Broader (1)

Genes

Papers overview

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2020
2020
Identification of miRNAs and the target genes related to male infertility and smoking using bioinformatics approaches
Abstract The impact of smoking on male fertility has been extensively acknowledged. Many studies have shown that smoking reduces… 
2018
2018
Correlation analyses revealed global microRNA–mRNA expression associations in human peripheral blood mononuclear cells
MicroRNAs (miRNAs) can regulate gene expression through binding to complementary sites in the 3′-untranslated regions of target… 
2017
2017
Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung
2017
2017
Structural characterisation of TNRC6A nuclear localisation signal in complex with importin-alpha
The GW182/TNRC6 family of proteins are central scaffolds that link microRNA-associated Argonaute proteins to the cytoplasmic… 
2017
2017
Establishment of human TNRC6A knockout cells and its transcriptome analysis
2016
2016
Abstract 3746: A high dose priming strategy with the novel RNAi therapeutic GS-10 elevates RISC Ago2, Ago4 and GW182 protein levels to enhance RNAi efficacy in a metastatic solid tumor model
A high initial priming dose of the novel RNAi therapeutic GS-10 was investigated as a strategy to elevate important RISC complex… 
Review
2013
Review
2013
The discovery of GW bodies.
Human autoantibodies were a key to the discovery of GW bodies and their integral protein, GW182. This publication marks the tenth… 
2012
2012
Epigenetics-related genes in prostate cancer: Expression profile in prostate cancer tissues, androgen-sensitive and -insensitive cell lines
Epigenetic changes have been suggested to drive prostate cancer (PCa) development and progression. Therefore, in this study, we… 
2011
2011
Trinucleotide Repeat Containing 6a (Tnrc6a)-mediated MicroRNA Function Is Required for Development of Yolk Sac Endoderm*
Background: Tnrc6a is involved for microRNA-mediated gene silencing in vitro. Results: Disruption of Tnrc6a results in defect in… 
2010
2010
Ago2 and GW182 expression in mouse preimplantation embryos: a link between microRNA biogenesis and GW182 protein synthesis.
MicroRNA-mediated RNA interference appears to play a role in early development and differentiation processes in preimplantation… 
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