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TNRC6A gene

Known as: CAGH26, trinucleotide repeat containing 6A, KIAA1460 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Genes

Papers overview

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Highly Cited
2019
Highly Cited
2019
Knockdown of TRIM65 inhibits autophagy and cisplatin resistance in A549/DDP cells by regulating miR-138-5p/ATG7
Cisplatin resistance is the main cause of treatment failure in patients with non-small-cell lung cancer (NSCLC). Autophagy is a… 
Highly Cited
2017
Highly Cited
2017
Multivalent Recruitment of Human Argonaute by GW182.
Highly Cited
2013
Highly Cited
2013
Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus.
GW182 family proteins play important roles in microRNA (miRNA)-mediated gene silencing. They interact with Argonaute (Ago… 
Highly Cited
2012
Highly Cited
2012
The Crystal Structure of Human Argonaute2
Human Argonaute Revealed RNA interference (RNAi) is mediated by Argonaute (Ago) proteins, which bind small regulatory RNAs that… 
Highly Cited
2012
Highly Cited
2012
Translational inhibition by deadenylation-independent mechanisms is central to microRNA-mediated silencing in zebrafish
MicroRNA (miRNA) is a class of small noncoding RNA approximately 22 nt in length. Animal miRNA silences complementary mRNAs via… 
Highly Cited
2010
Highly Cited
2010
Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
Highly Cited
2009
Highly Cited
2009
Axin determines cell fate by controlling the p53 activation threshold after DNA damage
In animals, P-bodies or GW-bodies appear to cause the congregation of proteins involved in microRNA (miRNA)-mediated post… 
Highly Cited
2009
Highly Cited
2009
Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression.
Proteins of the GW182 family play an important role in the execution of microRNA repression in metazoa. They interact directly… 
Highly Cited
2009
Highly Cited
2009
The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.
Proteins of the GW182 family are essential components of the miRNA pathway in animal cells. Vertebrate genomes encode three GW182… 
Highly Cited
2006
Highly Cited
2006
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes.
MicroRNAs (miRNAs) silence the expression of target genes post-transcriptionally. Their function is mediated by the Argonaute… 
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