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TNPO3 gene

Known as: TRANSPORTIN 3, IPO12, TRNSR 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BackgroundDespite intensive investigation the mechanism by which HIV-1 reaches the host cell nucleus is unknown. TNPO3, a… 
Highly Cited
2012
Highly Cited
2012
The HIV-1 genome enters cells inside a shell comprised of capsid (CA) protein. Variation in CA sequence alters HIV-1 infectivity… 
Highly Cited
2012
Highly Cited
2012
HIV-1 infection of macrophages plays a key role in viral pathogenesis and progression to AIDS. Polyinosine-polycytidylic acid… 
Highly Cited
2012
Highly Cited
2012
Background: TNPO3 is a key cellular factor involved in early steps of HIV-1 replication. Results: TNPO3 is highly structured… 
Highly Cited
2011
Highly Cited
2011
The HIV/AIDS pandemic is a major global health threat and understanding the detailed molecular mechanisms of HIV replication is… 
Highly Cited
2011
Highly Cited
2011
BackgroundHIV-1 infects non-dividing cells. This implies that the virus traverses the nuclear pore before it integrates into… 
Highly Cited
2009
Highly Cited
2009
ABSTRACT Recent genome-wide screens have highlighted an important role for transportin 3 in human immunodeficiency virus type 1… 
Highly Cited
2009
Highly Cited
2009
OBJECTIVE Interferon regulatory factor 5, an established susceptibility factor for systemic lupus erythematosus (SLE), plays a… 
Highly Cited
2008
Highly Cited
2008
HIV-1 exploits multiple host proteins during infection. We performed a large-scale small interfering RNA screen to identify host…