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TNFSF8 protein, human

Known as: CD30 Antigen Ligand, tumor necrosis factor (ligand) superfamily, member 8 protein, human, CD30L protein, human 
Tumor necrosis factor ligand superfamily member 8 (234 aa, ~26 kDa) is encoded by the human TNFSF8 gene. This protein plays a role in the induction… 
National Institutes of Health

Related topics

Related topics

15 relations
Apoptosis Regulatory ProteinsCell DeathCytokine GeneCytokine Receptor Binding

Broader (1)

CD30 Ligand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Ligands and receptors of the TNF superfamily are decreased in major depression and during early antidepressant therapy.
Review
2009
Review
2009
Targeting CD30/CD30L in oncology and autoimmune and inflammatory diseases.
The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF… 
Highly Cited
2009
Highly Cited
2009
Identification of gliotropic factors that induce human stem cell migration to malignant tumor.
Neural stem cells are mobile, are attracted to regions of brain damage, and can migrate a considerable distance to reach a glioma… 
2009
2009
CD153 in Rheumatoid Arthritis: Detection of a Soluble Form in Serum and Synovial Fluid, and Expression by Mast Cells in the Rheumatic Synovium
Objective. A CD30-CD153 mast cell axis has been described in skin inflammations and Hodgkin’s lymphoma. We investigated if a… 
2008
2008
Ex vivo simulation of IgG Fc and T‐cell receptor functions: An application to inflammatory bowel disease
Background: Human leukocyte IgG Fc receptors (Fc&ggr;R) and T‐cell receptors (TCR) are primary molecules involved in inflammatory… 
2007
2007
The radiation-induced cell-death signaling pathway is activated by concurrent use of cisplatin in sequential biopsy specimens from patients with cervical cancer
Objective: To identify changes in gene expression related to the concurrent use of platinum compounds with radiotherapy, in the… 
2007
2007
230: Functional analysis of interactive gene networks identifies survivin and TNFSF8 (apoptotic network) as key regulators in the process of uterine scarring
2003
2003
Selective Inhibition of Class Switching to IgG and IgE by Recruitment of the HoxC4 and Oct-1 Homeodomain Proteins and Ku70/Ku86 to Newly Identified ATTT cis-Elements*
Immunoglobulin (Ig) class switching is central to the maturation of the antibody response as IgG, IgA, and IgE are endowed with… 
2002
2002
CD30—Governor of Memory T Cells?
Abstract: CD30 is well recognized as a marker expressed by a heterogeneous group of lymphomas and in several immune and… 
Highly Cited
2000
Highly Cited
2000
Engagement of CD153 (CD30 Ligand) by CD30+ T Cells Inhibits Class Switch DNA Recombination and Antibody Production in Human IgD+ IgM+ B Cells1
CD153 (CD30 ligand) is a member of the TNF ligand/cytokine family expressed on the surface of human B cells. Upon exposure to IL… 
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