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TNFAIP6 gene

Known as: TSG6, TNF alpha induced protein 6, TSG-6 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
TNFα-stimulated protein 6 (TSG-6) reduces lung inflammation in an experimental model of bronchopulmonary dysplasia
BackgroundInflammation is a key factor in the pathogenesis of bronchopulmonary dysplasia (BPD). Tumor necrosis factor–stimulated… 
Highly Cited
2016
Highly Cited
2016
TSG-6 secreted by human umbilical cord-MSCs attenuates severe burn-induced excessive inflammation via inhibiting activations of P38 and JNK signaling
The hMSCs have become a promising approach for inflammation treatment in acute phase. Our previous study has demonstrated that… 
Highly Cited
2012
Highly Cited
2012
Secretome analysis of chondroitin sulfate-treated chondrocytes reveals anti-angiogenic, anti-inflammatory and anti-catabolic properties
IntroductionChondroitin sulfate (CS) is a symptomatic slow-acting drug for osteoarthritis (OA) widely used in the clinic. The aim… 
2008
2008
Hyaluronan Binding to Link Module of TSG-6 and to G1 Domain of Aggrecan Is Differently Regulated by pH*
The physiological functions of hyaluronan (HA) in the extracellular matrix of vertebrate tissues involve a range of specific… 
2006
2006
Evidence for a two-step mechanism involved in the formation of covalent HC x TSG-6 complexes.
IalphaI and TSG-6 interact to form a covalent bond between the C-terminal Asp alpha-carbon of an IalphaI heavy chain (HC) and an… 
2005
2005
TSG-6 Protein Binding to Glycosaminoglycans
TSG-6 protein, up-regulated in inflammatory lesions and in the ovary during ovulation, shows anti-inflammatory activity and plays… 
Highly Cited
1997
Highly Cited
1997
Growth factor and cytokine-regulated hyaluronan-binding protein TSG-6 is localized to the injury-induced rat neointima and confers enhanced growth in vascular smooth muscle cells.
Hyaluronan (HA) and HA-binding proteins have been implicated in a diverse array of biological processes, including development… 
1997
1997
Method for quantitative refolding of the link module from human TSG-6.
We have developed a procedure for the quantitative refolding of the Link module from human tumor necrosis factor-stimulated gene… 
1996
1996
TSG-6 expression in human articular chondrocytes. Possible implications in joint inflammation and cartilage degradation.
OBJECTIVE The hyaluronan-binding protein TSG-6 (tumor necrosis factor-stimulated gene 6) forms a stable complex with the serine… 
Highly Cited
1994
Highly Cited
1994
TSG-6, an arthritis-associated hyaluronan binding protein, forms a stable complex with the serum protein inter-alpha-inhibitor.
TSG-6 is a secreted 35-kDa glycoprotein, inducible by TNF and IL-1. The N-terminal portion of TSG-6 shows sequence homology to… 
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