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TNF receptor-associated factor 3

Known as: CRAF1 Protein, LAP-1 Protein, LMP1-associated protein 1 
A signal transducing tumor necrosis factor receptor associated factor that is involved in regulation of NF-KAPPA B signaling and activation of… 
National Institutes of Health

Related topics

Related topics

20 relations
B-Cell Immune Response PathwayCD40L Signaling PathwayIn BloodPositive Regulation of Apoptosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
DDX3 directly regulates TRAF3 ubiquitination and acts as a scaffold to coordinate assembly of signalling 2 complexes downstream of MAVS
13 The human DEAD-box helicase 3 (DDX3) has been shown to contribute to type I interferon induction 14 downstream of anti-viral… 
2015
2015
Estrogen receptor alpha inhibits RLR-mediated immune response via ubiquitinating TRAF3.
Highly Cited
2009
Highly Cited
2009
Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33)
Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33) 
2005
2005
TRAF interactions with raft‐like buoyant complexes, better than TRAF rates of degradation, differentiate signaling by CD40 and EBV latent membrane protein 1
The CD40 receptor and the Epstein‐Barr virus oncoprotein LMP1 are both members of the TNF‐receptor family and share several… 
2004
2004
FUNCTIONAL CHARACTERIZATION OF AN LCCL–LECTIN DOMAIN CONTAINING PROTEIN FAMILY IN PLASMODIUM BERGHEI
Using bioinformatic, proteomic, immunofluorescence, and genetic cross methods, we have functionally characterized a family of… 
Highly Cited
2000
Highly Cited
2000
Discrete Signaling Regions in the Lymphotoxin-β Receptor for Tumor Necrosis Factor Receptor-associated Factor Binding, Subcellular Localization, and Activation of Cell Death and NF-κB Pathways*
Lymphotoxin-β receptor (LTβR), a member of the tumor necrosis factor receptor superfamily, is essential for the development and… 
Highly Cited
1999
Highly Cited
1999
A scintillation proximity assay for the Raf/MEK/ERK kinase cascade: high-throughput screening and identification of selective enzyme inhibitors.
We have developed a quantitative scintillation proximity assay (SPA) that reproduces the Raf/MEK/ERK signal transduction pathway… 
Highly Cited
1999
Highly Cited
1999
Evidence of LMP1–TRAF3 interactions in glycosphingolipid‐rich complexes of lymphoblastoid and nasopharyngeal carcinoma cells
Latent membrane protein 1 (LMP1) is an Epstein‐Barr virus (EBV) protein expressed in EBV‐transformed B lymphocytes and in… 
1998
1998
Gene expression by single Reed-Sternberg cells: pathways of apoptosis and activation.
Although Hodgkin's disease is highly responsive to treatments that cause apoptosis, it remains resistant to the physiological… 
1998
1998
A single gene for human TRAF-3 at chromosome 14q32.3 encodes a variety of mRNA species by alternative polyadenylation, mRNA splicing and transcription initiation.
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