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TMPRSS2 gene
Known as:
TRANSMEMBRANE PROTEASE, SERINE 2
, PRSS10
, ETV1/TMPRSS2 Fusion Gene
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A fusion gene that results from a chromosomal translocation t(7;21)(p21;q22) which fuses the 5' end of the TMPRSS2 gene with exon 4 of the ETV1 gene…
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National Institutes of Health
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Related topics
Related topics
27 relations
Acinar Prostate Adenocarcinoma, Pseudohyperplastic Variant
Acinar Prostate Adenocarcinoma, Sarcomatoid Variant
Acinar Prostate Adenocarcinoma, Signet Ring Variant
Acinar Prostate Mucinous Adenocarcinoma
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TMPRSS2 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Prostate cancer: Mastering transcription: TMPRSS2–ERG and the cis-regulatory landscape
L. Stone
Nature reviews. Urology
2017
Corpus ID: 31673849
Genetics provide insight into the molecular processes driving ERG overexpression in prostate cancer. Moreover the effects of…
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2015
2015
[Relationship between TMPRSS2: ERG and the pathological grade of prostate cancer].
Fa-xian Yi
,
Hong Li
,
Q. Wei
,
Xiang Li
,
H. Zeng
Zhonghua nan ke xue = National journal of…
2015
Corpus ID: 19802732
OBJECTIVE To study the relationship between TMPRSS2: ERG gene fusion and the pathological grade of prostate cancer (PCa…
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Review
2014
Review
2014
Re: TMPRSS2-ERG Gene Fusions Induce Prostate Tumor- igenesis by Modulating MicroRNA miR-200c
L. Türkeri
,
J. Kim
,
Wu
2014
Corpus ID: 260879235
SA. Risk stratification of patients with extraprostatic extension and negative lymph nodes at radical prostatectomy: identifying…
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2013
2013
Influenza pseudotype production with TMPRSS2
Nigel James Temperton
2013
Corpus ID: 87297730
Review
2012
Review
2012
t(8;21)(q24;q22) in prostate cancer
Dorothee Pflueger
2012
Corpus ID: 85434200
Review on t(8;21)(q24;q22) in prostate cancer, with data on clinics, and the genes involved.
2011
2011
[Detection and significance of fusion gene between TMPRSS2 and ETS transcription factor genes in fresh prostatic cancer tissues in Chinese patients].
Hua Xiang
,
Zong-xin Ling
,
K. Sun
,
G. Ren
,
Q. You
,
Xiong-Zeng Zhu
Zhonghua bing li xue za zhi = Chinese journal of…
2011
Corpus ID: 26456249
近年学者发现,大多数前列腺癌中跨膜丝氨酸蛋白酶2(TMPRSS2)基因与ETS转录因子家族的ERG、ETV1或ETV4之间可以发生融合,形成融合基因TMPRSS2-ERG、-ETV1和-ETV4(此型极少见),且它们可能还是重要预后指标[1-3…
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2011
2011
Molecular analysis of multifocal prostate cancer cases
R. Sabaliauskaitė
,
D. Petroška
,
+4 authors
S. Jarmalaitė
2011
Corpus ID: 72632226
Background. Prostate cancer (PCa) is usually a multifocal disease with different foci displaying histological and molecular…
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2010
2010
Abstract 3240: A transgenic mouse model of a common genetic aberration in prostate cancer: Chromosomal rearrangement of TMPRSS2:ERG
O. Casey
,
Hibah O. Awwad
,
+5 authors
K. Kelly
2010
Corpus ID: 75212167
The most prevalent gene fusion identified in prostate cancer (PC) to date is the recurrent fusion of the 5’ region of…
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2008
2008
Abstract A91: Obesity and the TMPRSS2:ERG translocation in prostate cancer
L. Mucci
,
Jing Ma
,
+4 authors
P. Kantoff
2008
Corpus ID: 76594989
A91 Background The recently identified TMPRSS2:ERG translocation is an early and common somatic event in prostate cancer…
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Review
2008
Review
2008
Molecular Genetic Etiology of Prostate Cancer
V. Pethe
,
B. Bapat
2008
Corpus ID: 18528597
Prostate Cancer (PCa) is the most frequently diagnosed non-skin cancer and second leading cause of cancer deaths after lung…
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