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TMPRSS2 gene
Known as:
TRANSMEMBRANE PROTEASE, SERINE 2
, PRSS10
, ETV1/TMPRSS2 Fusion Gene
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A fusion gene that results from a chromosomal translocation t(7;21)(p21;q22) which fuses the 5' end of the TMPRSS2 gene with exon 4 of the ETV1 gene…
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National Institutes of Health
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Related topics
Related topics
27 relations
Acinar Prostate Adenocarcinoma, Pseudohyperplastic Variant
Acinar Prostate Adenocarcinoma, Sarcomatoid Variant
Acinar Prostate Adenocarcinoma, Signet Ring Variant
Acinar Prostate Mucinous Adenocarcinoma
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TMPRSS2 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
TMPRSS2 Transcriptional Inhibition as a Therapeutic Strategy for COVID-19
Xinchen Wang
,
R. Dhindsa
,
+6 authors
D. Goldstein
2020
Corpus ID: 218551098
There is an urgent need to identify effective therapies for COVID-19. The SARS-CoV-2 host factor protease TMPRSS2 is required for…
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2020
2020
Targeting the entry step of SARS-CoV-2: a promising therapeutic approach
Jing Li
,
P. Zhan
,
Xinyong Liu
Signal Transduction and Targeted Therapy
2020
Corpus ID: 219710442
A very recent study published in Cell by Hoffmann and coworkers identifies the key proteins exploited by SARS-CoV-2 to invade…
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2017
2017
Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases.
J. C. Reid
,
Admire Matsika
,
+7 authors
J. Hooper
American Journal of Cancer Research
2017
Corpus ID: 41995687
We provide evidence of a pericellular network of proteases that are elevated and co-expressed in prostate cancer. The network…
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2014
2014
Conserved Two-Step Regulatory Mechanism of Human Epithelial Differentiation
J. Rane
,
A. Droop
,
+5 authors
N. Maitland
Stem Cell Reports
2014
Corpus ID: 262362826
2014
2014
ERG and CHD1 heterogeneity in prostate cancer: Use of confocal microscopy in assessment of microscopic foci
Irina V. Tereshchenko
,
H. Zhong
,
+9 authors
R. DiPaola
The Prostate
2014
Corpus ID: 12033442
Biomarkers predicting tumor response are important to emerging targeted therapeutics. Complimentary methods to assess and…
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2013
2013
Targeted disruption of the p160 coactivator interface of androgen receptor (AR) selectively inhibits AR activity in both androgen-dependent and castration-resistant AR-expressing prostate cancer…
Manjula Nakka
,
I. Agoulnik
,
N. Weigel
International Journal of Biochemistry and Cell…
2013
Corpus ID: 36763322
2013
2013
A novel four-color fluorescence in situ hybridization assay for the detection of TMPRSS2 and ERG rearrangements in prostate cancer.
X. Qu
,
Grace Randhawa
,
+9 authors
M. Fang
Cancer Genetics
2013
Corpus ID: 2077792
2010
2010
On the use of prostate-specific antigen for screening of prostate cancer in European Randomised Study for Screening of Prostate Cancer.
C. Bangma
,
R. V. van Schaik
,
B. G. Blijenberg
,
M. Roobol
,
H. Lilja
,
U. Stenman
European Journal of Cancer
2010
Corpus ID: 36012968
Review
2009
Review
2009
Translocations in epithelial cancers.
J. Brenner
,
A. Chinnaiyan
Biochimica et Biophysica Acta
2009
Corpus ID: 29185594
Highly Cited
2008
Highly Cited
2008
Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG‐positive prostate cancer
M. Björkman
,
K. Iljin
,
+4 authors
O. Kallioniemi
International Journal of Cancer
2008
Corpus ID: 37867732
Gene fusions between prostate‐specific, androgen responsive TMPRSS2 gene and oncogenic ETS factors, such as ERG, occur in up to…
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