TMPRSS2 gene

Known as: TRANSMEMBRANE PROTEASE, SERINE 2, PRSS10, ETV1/TMPRSS2 Fusion Gene 
A fusion gene that results from a chromosomal translocation t(7;21)(p21;q22) which fuses the 5' end of the TMPRSS2 gene with exon 4 of the ETV1 gene… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Chromosomal rearrangements fusing the androgen-regulated gene TMPRSS2 to the oncogenic ETS transcription factor ERG occur in… (More)
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Highly Cited
2009
Highly Cited
2009
A significant number of prostate cancers have been shown to have recurrent chromosomal rearrangements resulting in the fusion of… (More)
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Highly Cited
2008
Highly Cited
2008
New predictive markers for managing prostate cancer are urgently required because of the highly variable natural history of this… (More)
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Highly Cited
2008
Highly Cited
2008
Recurrent gene fusions involving oncogenic ETS transcription factors (including ERG, ETV1, and ETV4) have been identified in a… (More)
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Highly Cited
2008
Highly Cited
2008
Recurrent gene fusions between the androgen-regulated gene TMPRSS2 and the ETS transcription factor family members ERG, ETV1, and… (More)
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Highly Cited
2007
Highly Cited
2007
Novel recurrent gene fusions between the androgen-regulated gene TMPRSS2 and the ETS family members ERG, ETV1, or ETV4 have been… (More)
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Highly Cited
2007
Highly Cited
2007
TMPRSS2-ERG gene fusions have recently been reported to be present in a high proportion of human prostate cancers. In the current… (More)
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Highly Cited
2006
Highly Cited
2006
Prostate cancer is a common and clinically heterogeneous disease with marked variability in progression. The recent… (More)
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Highly Cited
2006
Highly Cited
2006
Recent studies have reported that the majority of prostate cancers express fusion genes in which the 5' region of the androgen… (More)
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Highly Cited
2005
Highly Cited
2005
Recurrent chromosomal rearrangements have not been well characterized in common carcinomas. We used a bioinformatics approach to… (More)
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