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TLX3 gene

Known as: T-cell leukemia homeobox 3, HOX11L2, HOMEOBOX 11-LIKE 2 
This gene may be involved in transcriptional regulation.
National Institutes of Health

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Related topics

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Cell Differentiation processHomo sapiensPattern FormationT-Cell Leukemia Homeobox Protein 3

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TLX3 wt Allele

Papers overview

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2018
2018
Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia
2014
2014
Readmissions after major urologic cancer surgery.
INTRODUCTION We examine the incidence and predictors of readmission after major urologic cancer surgery using a national… 
2012
2012
Simultaneous Translocation of Both TCR Loci (14q11) with Rare Partner Loci (Xq22 and 12p13) in a Case of T-lymphoblastic Leukemia
The most common recurrent cytogenetic abnormalities in T-lymphoblastic leukemia (T-acute lymphoblastic leukemia [T-ALL]) involve… 
2008
2008
Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group
Adult T-cell acute lymphoblastic leukemia (T-ALL) continues to represent an unfavorable disease. Molecularly based treatment… 
Review
2007
Review
2007
Acquired chromosomal rearrangements targeting selected transcription factors: contribution of molecular cytogenetic and expression analyses to the identification of clinically and biologically…
In leukemias chromosomal aberrations, balanced translocations in particular, play a critical role in the oncogenic process. The… 
2003
2003
Exclusion of RNX as a major gene in congenital central hypoventilation syndrome (CCHS, Ondine's curse)
Congenital central hypoventilation syndrome (CCHS) is a rare condition for which segregation analyses have suggested genetic… 
2002
2002
High incidence of Hox11L2 expression in children with T-ALL
The orphan homeobox gene HOX11L2 was previously found to be transcriptionally activated as a result of the t(5;14)(q35;q32… 
2002
2002
Mutational analysis of the RNX gene in congenital central hypoventilation syndrome.
Congenital central hypoventilation syndrome (CCHS) is a rare syndrome characterized by failure of autonomic respiratory control… 
2002
2002
HOX 11 L 2 expression defines a clinical subtype of pediatric TALL associated with poor prognosis
The most frequent oncogenic activation events characterized in childhood T acute lymphoblastic leukemia (T-ALL) result in the… 
2001
2001
Assignment1 of the HOX11L2 gene to human chromosome band 5q35.1 and of its murine homolog to mouse chromosome bands 11A4–A5 by in situ hybridization
The homeobox (Hox) gene family is represented by both clustered and unclustered genes whose products are characterized by the… 
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