Skip to search formSkip to main contentSkip to account menu

TLR9 gene

Known as: toll like receptor 9, Toll-Like Receptor 9 Gene, CD289 
This gene plays a role in innate immunity.
National Institutes of Health

Related topics

Related topics

7 relations
ImmunityInterferon Signaling ProcessInterleukin Signaling ProcessLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Association study of TLR-9 polymorphisms and systemic lupus erythematosus in northern Chinese Han population.
2011
2011
Negative regulation of signaling by a soluble form of toll‐like receptor 9
Nucleic acid structures are highly conserved through evolution and when self nucleic acids are aberrantly detected by toll‐like… 
Highly Cited
2009
Highly Cited
2009
Requirement for DNA CpG Content in TLR9-Dependent Dendritic Cell Activation Induced by DNA-Containing Immune Complexes1
Although TLR9 was originally thought to specifically recognize microbial DNA, it is now evident that mammalian DNA can be an… 
2008
2008
Impaired Naive and Memory B-Cell Responsiveness to TLR9 Stimulation in Human Immunodeficiency Virus Infection
ABSTRACT Toll-like receptor 9 (TLR9) agonists such as unmethylated bacterial CpG DNAs activate B lymphocytes directly… 
Highly Cited
2007
Highly Cited
2007
Gut‐derived commensal bacterial products inhibit liver dendritic cell maturation by stimulating hepatic interleukin‐6/signal transducer and activator of transcription 3 activity
Intraorgan dendritic cells (DCs) monitor the environment and help translate triggers of innate immunity into adaptive immune… 
Highly Cited
2007
Highly Cited
2007
Clinical setbacks for toll-like receptor 9 agonists in cancer
Cancer failures are not deterring interest in toll-like receptor agonists for other high profile indications. 
Highly Cited
2006
Highly Cited
2006
Cytoplasmic Targeting Motifs Control Localization of Toll-like Receptor 9*
Toll-like receptors (TLRs) are essential for host defense. Although several TLRs reside on the cell surface, nucleic acid… 
Review
2005
Review
2005
Progress in drug development of immunostimulatory CpG oligodeoxynucleotide ligands for TLR9
Oligodeoxynucleotides (ODNs) with unmethylated deoxycytosine-deoxyguanosine (CpG) motifs are recognised by Toll-like receptor… 
2004
2004
Role of vav1- and src-related Tyrosine Kinases in Macrophage Activation by CpG DNA*
Macrophage activation by CpG DNA requires toll-like receptor 9 and the adaptor protein MyD88. Gram-negative bacterial… 
Highly Cited
2003
Highly Cited
2003
Toll-Like Receptor 2 (TLR2) and TLR9 Signaling Results in HIV-Long Terminal Repeat Trans-Activation and HIV Replication in HIV-1 Transgenic Mouse Spleen Cells: Implications of Simultaneous Activation…
Opportunistic infections are common in HIV-infected patients; they activate HIV replication and contribute to disease progression… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)