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TLE4 gene

Known as: E(spI), TLE4, transducin like enhancer of split 4 
This gene plays a role in Notch and Wnt signaling pathways and transcriptional repression.
National Institutes of Health

Related topics

Related topics

9 relations
Signal TransductionTLE1 geneTLE2 geneTLE3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Type 2 diabetes genetic risk variants and gestational diabetes
Objective: Gestational diabetes (GDM) is defined as any degree of glucose intolerance first diagnosed in pregnancy. Glucose… 
2017
2017
Acute myeloid leukemia with del(9q) is characterized by frequent mutations of NPM1, DNMT3A, WT1 and low expression of TLE4
Deletions of the long arm of chromosome 9 [del(9q)] are a rare but recurring aberration in acute myeloid leukemia (AML). Del(9q… 
2016
2016
Detection of Novel Genomic Markers for Predicting Prognosis in Hepatocellular Carcinoma Patients by Integrative Analysis of Copy Number Aberrations and Gene Expression Profiles: Results from a Long…
The aim of this study was to explore novel genomic biomarkers predicting hepatocellular carcinoma (HCC) prognosis by integrative… 
2012
2012
Tle4 Is Critical for Proper B- Cell Differentiation and Maintenance of the Murine Bone Marrow Niche
Abstract 1202 Transducin-like/Enhancer of Split 4 ( TLE4 ), a homolog of the master developmental regulator in Drosophila… 
2011
2011
بررسی بیان ژنهای گیرندههای شبهتول ۲ و ۴ (TLE4 & TLR2) در سلولهای تکهستهای خون محیطی (PBMCs) گاوهای مبتلا به یون با روش (Quantitative Real - time (qPCR
Highly Cited
2007
Highly Cited
2007
The roles of Groucho/Tle in left-right asymmetry and Kupffer's vesicle organogenesis.
2006
2006
Differential expression profiling of genes in a complete hydatidiform mole using cDNA microarray analysis.
2005
2005
Duplicated members of the Groucho/Tle gene family in fish
The highly conserved Groucho/Tle gene family has widespread functions during embryonic development and in adults. For mammalians… 
2005
2005
TLE Corepressors as Novel Candidate AML Tumor Suppressor Genes That Regulate Wnt Signaling, Cell Cycle Progression, and Myeloid Differentiation.
Deletion of the long arm of chromosome 9, del(9q), is one of the most common mutations associated with t(8;21) AML. Up to 50% of… 
2002
2002
A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes
During mouse B‐cell development, Pax5 is an essential transcription factor that acts as an activator of B‐cell‐specific genes and… 
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