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TK Gene
Known as:
Thymidine Kinase Gene
The TK Gene encodes thymidine kinase, a transferase class pyrimidine salvage enzyme that catalyzes ATP-dependent phosphorylation of thymine…
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National Institutes of Health
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Papers overview
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Highly Cited
1989
Highly Cited
1989
Germline transmission of exogenous genes in the chicken.
R. Bosselman
,
R. Hsu
,
+7 authors
F. Jacobsen
Science
1989
Corpus ID: 36560432
Difficulties associated with in vitro manipulation and culture of the early chicken embryo have restricted generation of…
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Highly Cited
1985
Highly Cited
1985
Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eukaryotic mRNA reduces translational efficiency
J. Pelletier
,
N. Sonenberg
Cell
1985
Corpus ID: 22717376
Highly Cited
1984
Highly Cited
1984
Expression of rabies virus glycoprotein from a recombinant vaccinia virus
M. Kieny
,
R. Lathe
,
+6 authors
J. Lecocq
Nature
1984
Corpus ID: 30183
Rabies is one of the oldest diseases known to man, but its successful control has remained elusive. Although effective vaccines…
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Highly Cited
1984
Highly Cited
1984
Human thymidine kinase gene: molecular cloning and nucleotide sequence of a cDNA expressible in mammalian cells
H. Bradshaw
,
P. Deininger
Molecular and Cellular Biology
1984
Corpus ID: 22863276
A cDNA containing the entire coding region of the human thymidine kinase gene has been molecularly cloned. The cDNA is under the…
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Highly Cited
1982
Highly Cited
1982
Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus.
D. Panicali
,
E. Paoletti
Proceedings of the National Academy of Sciences…
1982
Corpus ID: 21323043
We have constructed recombinant vaccinia viruses containing the thymidine kinase gene from herpes simplex virus. The gene was…
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Highly Cited
1982
Highly Cited
1982
In vitro methylation of the hamster adenine phosphoribosyltransferase gene inhibits its expression in mouse L cells.
R. Stein
,
A. Razin
,
H. Cedar
Proceedings of the National Academy of Sciences…
1982
Corpus ID: 40589383
The effect of DNA methylation on the expression of the hamster adenine phosphoribosyltransferase (aprt) gene in mouse cells has…
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Highly Cited
1982
Highly Cited
1982
A synthetic heat‐shock promoter element confers heat‐inducibility on the herpes simplex virus thymidine kinase gene.
H. Pelham
,
M. Bienz
EMBO Journal
1982
Corpus ID: 12402998
Previous deletion analysis of the Drosophila hsp70 heat‐shock promoter has identified a sequence upstream of the TATA box that is…
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Highly Cited
1981
Highly Cited
1981
A new dominant hybrid selective marker for higher eukaryotic cells.
F. Colbère-Garapin
,
F. Horodniceanu
,
P. Kourilsky
,
A. Garapin
Journal of Molecular Biology
1981
Corpus ID: 39755166
Highly Cited
1981
Highly Cited
1981
Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.
M. Wagner
,
J. A. Sharp
,
W. Summers
Proceedings of the National Academy of Sciences…
1981
Corpus ID: 41550853
We have determined the complete nucleotide sequence of the thymidine kinase (ATP:thymidine 5' phosphotransferase, EC 2.7.1.21…
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Highly Cited
1980
Highly Cited
1980
Excretion of hepatitis B surface antigen particles from mouse cells transformed with cloned viral DNA.
M. Dubois
,
C. Pourcel
,
S. Rousset
,
C. Chany
,
P. Tiollais
Proceedings of the National Academy of Sciences…
1980
Corpus ID: 38302490
A plasmid containing two cloned hepatitis B virus genomes in a tandem head-to-tail arrangement has been introduced into mouse…
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