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TIC10 compound

Known as: TIC10, TRAIL-inducing compound 10 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Heterocyclic Compounds, 4 or More Rings

Narrower (1)

ONC201

Papers overview

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2020
2020
Imipridone enhances vascular relaxation via FOXO1 pathway
Cardiovascular complications are a side effect of cancer therapy, potentially through reduced blood vessel function. ONC201… 
2017
2017
Imipridone family on successful TRAIL
Identification of candidate cancer therapeutic small molecule activators of the TRAIL gene was the primary goal that led to… 
2016
2016
Mikhail E. Elyashberg and Antony J. Williams: Computer-based structure elucidation from spectral data: the art of solving problems
2016
2016
Abstract 349: Structure-activity relationships and mechanistic analysis of analogues of the clinical-stage anti-cancer small molecule ONC201
TRAIL is an endogenous protein that initiates apoptosis selectively in cancer without toxic side effects, prompting interest in… 
2013
2013
Small-molecule drug drives cancer cells to suicide
Studies in mice show therapy is effective even in hard-to-treat brain tumours. 
2013
2013
Abstract 3732: Therapeutic targeting of colorectal cancer stem cells by TRAIL-inducing small molecule TIC10.
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the USA. A growing body of evidence indicates that CRC… 
2013
2013
Abstract 2949: Characterization of TIC10, a novel small molecule inducer of TRAIL, in combination with chemotherapy for lymphomain vitro.
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC TNF-related apoptosis inducing ligand (TRAIL; Apo2L… 
2013
2013
Preparation and Properties of TiC10 /Cu-Al_2O_3 Composite Fabricated by Vacuum Hot Pressing
  • Z. Yi
  • 2013
  • Corpus ID: 138343767
TiC10 /Cu-Al2O3 composite was prepared by vacuum hot pressing sintering process,its properties and microstructure were tested.The… 
2013
2013
Abstract LB-307: TRAIL-inducing agent -TIC10 and combinatorial therapeutics in pediatric lymphoma: a targeted approach.
Despite significant progress in 5-year survival rates for Non-Hodgkin9s Lymphoma (NHL) using conventional treatment standards… 
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