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TGN-1412 monoclonal antibody

Known as: TGN 1412, monoclonal antibody TGN1412, TAB08 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Antibodies, Monoclonal, Humanized

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Author response for "Human Fcγ receptors compete for TGN1412 binding which determines the antibody's effector function"
2018
2018
Katastrofa u ispitivanju I. faze sa "superagonistom" TGN1412
2018
2018
Faculty Opinions recommendation of The rise and fall of the CD28 superagonist TGN1412 and its return as TAB08: a personal account.
2013
2013
This information is current as PreClinical Testing of Immunotherapeutics Understanding the Causes to Improve Monoclonal Antibody TGN1412: Better ''Cytokine Storm'' in the Phase I Trial of
and Stephen PooleJ. Thorpe, Adrian Bristow, Meenu Wadhwa, Robin ThorpeTarrant, Jane Robinson, Tony Meager, Carl Dolman, Susan… 
Review
2007
Review
2007
Review of New Challenges for the Development of Early Phase Biologic Compounds in the Wake of the TGN1412 Clinical Trial
2006
2006
Will volunteers still want to take part in research after the TGN1412 trial
2006
2006
[New catastrophe in pharmacological treatment--the crisis of clinical studies? Acute organ failure after administration of TGN1412].
2006
2006
Drug giants hamstrung by timid middle management
SIR — Your News story about the recent clinical-trial disaster, “Can super-antibody drugs be tamed?” (Nature 440, 855–856; 2006… 
2006
2006
Disaster in phase I clinical trial with TGN1412 superagonist
This paper describes phase I clinical trial, which ended with cytokine storm and life-threatening adverse events in 6… 
2006
2006
TGN1412: Superagonist Dr. Jekyll and Superantigen Mr. Hyde
Los anticuerpos anti-CD28 superagonistas inducen activación de los linfocitos T en ausencia de estimulación del TCR. Los ensayos… 
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