Skip to search formSkip to main contentSkip to account menu

TGFBRAP1 gene

Known as: TRAP1, TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1, VPS3 CORVET complex subunit 
National Institutes of Health

Related topics

Related topics

1 relation
TNF receptor-associated factor 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The variant at TGFBRAP1 is significantly associated with type 2 diabetes mellitus and affects diabetes‐related miRNA expression
While the transforming growth factor‐β1 (TGF‐β1) regulates the growth and proliferation of pancreatic β‐cells, its receptors… 
2017
2017
Compound useful as trap1 inhibitor, and anticancer composition containing same
The present invention relates to a compound simultaneously inhibiting a heat shock protein Hsp90 and a Hsp90 homologous protein… 
2016
2016
5′‐N‐ethylcarboxamidoadenosine is not a paralog‐specific Hsp90 inhibitor
The molecular chaperone Hsp90 facilitates the folding and modulates activation of diverse substrate proteins. Unlike other heat… 
2016
2016
2.4 Å resolution crystal structure of human TRAP1NM, the Hsp90 paralog in the mitochondrial matrix.
TRAP1 is an organelle-specific Hsp90 paralog that is essential for neoplastic growth. As a member of the Hsp90 family, TRAP1 is… 
2014
2014
Correction: Genomic Restructuring in the Tasmanian Devil Facial Tumour: Chromosome Painting and Gene Mapping Provide Clues to Evolution of a Transmissible Tumour
An error was made in record keeping at the very start of this study regarding the strain classification of four of the tumour… 
2012
2012
Abstract 5742: Up-regulation of mitochondrial chaperone TRAP1 in cancer precursors associated with chronic inflammation
Chronic ulcerative colitis (UC) is an inflammatory bowel disease that predisposes to colorectal cancer. In chronic UC patients… 
2010
2010
Cancer esearch apeutics , Targets , and Chemical Biology chondrial Chaperone Trap 1 and the Calcium Binding tein Sorcin Interact and Protect Cells against Apoptosis R ced by Antiblastic Agents
nloaded P1, a mitochondrial chaperone (Hsp75) with antioxidant and antiapoptotic functions, is involved in rug resistance in… 
2008
2008
Pdr5-mediated multidrug resistance requires the CPY-vacuolar sorting protein Vps3: are xenobiotic compounds routed from the vacuole to plasma membrane transporters for efflux?
In Saccharomyces cerevisiae several members of the ATP-binding cassette transporter superfamily efflux a broad range of… 
2005
2005
Changes in spatial and temporal localization of Dictyostelium homologues of TRAP1 and GRP94 revealed by immunoelectron microscopy.
2004
2004
Contribution of PAR-1, PAR-4 and GPIbα in intracellular signaling leading to the cleavage of the β3 cytoplasmic domain during thrombin-induced platelet aggregation
Summary Integrin αIIbβ3 plays a pivotal role in platelet aggregation by binding to fibrinogen. The β3 cytoplasmic domain of αIIb… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)