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TET1 gene

Known as: LCX, CXXC FINGER PROTEIN 6, KIAA1676 
This gene is involved in the regulation of DNA methylation.
National Institutes of Health

Related topics

Related topics

5 relations
CXXC5 geneDNA Methylation RegulationMethylcytosine Dioxygenase TET1Oxidation-Reduction

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TET1 wt Allele

Papers overview

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Highly Cited
2013
Highly Cited
2013
Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons
Axonal Actin How actin is organized in the axons and dendrites of neurons is largely unknown. Xu et al. (p. 452, published online… 
Highly Cited
2013
Highly Cited
2013
Nanog-dependent function of Tet1 and Tet2 in establishment of pluripotency
Molecular control of the pluripotent state is thought to reside in a core circuitry of master transcription factors including the… 
Highly Cited
2011
Highly Cited
2011
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
Enzymes catalysing the methylation of the 5-position of cytosine (mC) have essential roles in regulating gene expression and… 
Highly Cited
2011
Highly Cited
2011
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
Epigenetic modification of the mammalian genome by DNA methylation (5-methylcytosine) has a profound impact on chromatin… 
Highly Cited
2011
Highly Cited
2011
Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain
Highly Cited
2011
Highly Cited
2011
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.
Highly Cited
2011
Highly Cited
2011
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.
Highly Cited
2011
Highly Cited
2011
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.
Highly Cited
2010
Highly Cited
2010
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
DNA methylation is one of the best-characterized epigenetic modifications. Although the enzymes that catalyse DNA methylation… 
Highly Cited
2009
Highly Cited
2009
Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.
Disease alleles that activate signal transduction are common in myeloid malignancies; however, there are additional unidentified… 
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