TET1 gene

Known as: LCX, CXXC FINGER PROTEIN 6, KIAA1676 
This gene is involved in the regulation of DNA methylation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
DNA hydroxylation catalyzed by Tet dioxygenases occurs abundantly in embryonic stem cells and neurons in mammals. However, its… (More)
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Highly Cited
2013
Highly Cited
2013
The ten-eleven translocation (Tet) family of methylcytosine dioxygenases catalyze oxidation of 5-methylcytosine (5mC) to 5… (More)
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Highly Cited
2011
Highly Cited
2011
Enzymes catalysing the methylation of the 5-position of cytosine (mC) have essential roles in regulating gene expression and… (More)
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Highly Cited
2011
Highly Cited
2011
Cytosine methylation is the major covalent modification of mammalian genomic DNA and plays important roles in transcriptional… (More)
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Highly Cited
2011
Highly Cited
2011
TET family enzymes convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. Here, we show that Tet1 and Tet2 are… (More)
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Highly Cited
2011
Highly Cited
2011
Epigenetic modification of the mammalian genome by DNA methylation (5-methylcytosine) has a profound impact on chromatin… (More)
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Highly Cited
2011
Highly Cited
2011
DNA methylation at the 5 position of cytosine (5mC) in the mammalian genome is a key epigenetic event critical for various… (More)
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Highly Cited
2011
Highly Cited
2011
The Tet family of enzymes (Tet1/2/3) converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). Mouse embryonic stem… (More)
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Highly Cited
2009
Highly Cited
2009
DNA cytosine methylation is crucial for retrotransposon silencing and mammalian development. In a computational search for… (More)
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Highly Cited
2009
Highly Cited
2009
Disease alleles that activate signal transduction are common in myeloid malignancies; however, there are additional unidentified… (More)
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