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TEMPOL-H
Known as:
HOTMP
, 4-hydroxy-2,2,6,6-tetramethyl-1-hydroxypiperidine
, 4-hydroxy-TEMPO
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Cyclic N-Oxides
Hydroxylamine
Narrower (1)
OT-674
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Synthesis, characterization, and radioprotective activity of α,β-unsaturated aryl sulfone analogs and their Tempol conjugates.
Nan Zhou
,
Tian Feng
,
+6 authors
Hui Chen
MedChemComm
2017
Corpus ID: 52002201
Some novel α,β-unsaturated aromatic sulfone analogs (5a-5m) and their Tempol conjugates (6a-6e) have been synthetically prepared…
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2011
2011
Inhibition of the chlorinating activity of myeloperoxidase by tempol: revisiting the kinetics and mechanisms.
R. Queiroz
,
S. Vaz
,
O. Augusto
The Biochemical journal
2011
Corpus ID: 41437824
The nitroxide tempol (4-hydroxy-2,2,6,6-tetramethyl piperidine-1-oxyl) reduces tissue injury in animal models of inflammation by…
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Highly Cited
2008
Highly Cited
2008
Role of Oxidant Stress on AT1 Receptor Expression in Neurons of Rabbits With Heart Failure and in Cultured Neurons
Dongmei Liu
,
Lie Gao
,
S. Roy
,
K. Cornish
,
I. Zucker
Circulation research
2008
Corpus ID: 199744
We have previously reported that the expression of Angiotensin II (Ang II) type 1 receptors (AT1R) was increased in the rostral…
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2008
2008
Formation of TEMPOL-hydroxylamine during reaction between TEMPOL and hydroxyl radical: HPLC/ECD study
Wataru Kudo
,
M. Yamato
,
+4 authors
H. Utsumi
Free radical research
2008
Corpus ID: 29144429
Nitroxyl radicals are important antioxidants that have been used to protect animal tissues from oxidative damage. Their reaction…
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Highly Cited
2006
Highly Cited
2006
Local treatment of experimental colitis in the rat by negatively charged liposomes of catalase, TMN and SOD
T. Jubeh
,
Mirela Nadler-Milbauer
,
Y. Barenholz
,
A. Rubinstein
Journal of drug targeting
2006
Corpus ID: 37063417
Superoxide dismutase (SOD), 4-amino tempol (tempamine, denoted as TMN) and catalase were encapsulated into negatively charged…
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2004
2004
Central Tempol alters basal sympathetic nerve discharge and attenuates sympathetic excitation to central ANG II.
Ning Lu
,
B. Helwig
,
R. Fels
,
S. Parimi
,
M. Kenney
American journal of physiology. Heart and…
2004
Corpus ID: 13468026
In the present study, we established dose-response relationships between central administration of 4-hydroxy-2,2,6,6…
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2004
2004
4-Hydroxy tempol-induced impairment of mitochondrial function and augmentation of glucose transport in vascular endothelial and smooth muscle cells.
E. Alpert
,
H. Altman
,
+4 authors
S. Sasson
Biochemical pharmacology
2004
Corpus ID: 26252803
2002
2002
The effects of derivatives of the nitroxide tempol on UVA-mediated in vitro lipid and protein oxidation.
E. Damiani
,
R. Castagna
,
L. Greci
Free radical biology & medicine
2002
Corpus ID: 29333087
Highly Cited
2001
Highly Cited
2001
Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity.
S. X. Liu
,
M. Athar
,
I. Lippai
,
C. Waldren
,
T. Hei
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 28732768
Although arsenic is a well-established human carcinogen, the mechanisms by which it induces cancer remain poorly understood. We…
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Highly Cited
1992
Highly Cited
1992
Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide.
M. Krishna
,
D. Grahame
,
A. Samuni
,
J. Mitchell
,
A. Russo
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 29920698
Dismutation of superoxide has been shown previously to be catalyzed by stable nitroxide compounds. In the present study, the…
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