FAQ

TEMPOL-H

Known as: HOTMP, 4-hydroxy-2,2,6,6-tetramethyl-1-hydroxypiperidine, 4-hydroxy-TEMPO 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
01219922018

Related topics

Related topics

3 relations

Broader (2)

Cyclic N-OxidesHydroxylamine

Narrower (1)

OT-674

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
TEMPOL-H
Cyclic N-Oxides
Hydroxylamine
OT-674

Papers overview

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2015
2015
EGF receptor deletion in podocytes attenuates diabetic nephropathy.
The generation of reactive oxygen species (ROS), particularly superoxide, by damaged or dysfunctional mitochondria has been… (More)
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2013
2013
Impairment of pancreatic β-cell function by chronic intermittent hypoxia.
NEW FINDINGS What is the central question of this study? Periodic decreases in arterial blood O2 or chronic intermittent hypoxia… (More)
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2012
2012
Chronic intermittent hypoxia increases apnoea index in sleeping rats.
Intermittent hypoxia (IH) is the dominant feature of sleep-disordered breathing which is very common. It is recognized that IH… (More)
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2011
2011
Inhibition of the chlorinating activity of myeloperoxidase by tempol: revisiting the kinetics and mechanisms.
The nitroxide tempol (4-hydroxy-2,2,6,6-tetramethyl piperidine-1-oxyl) reduces tissue injury in animal models of inflammation by… (More)
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2010
2010
Acute lead-induced vasoconstriction in the vascular beds of isolated perfused rat tails is endothelium-dependent.
Chronic lead exposure induces hypertension in humans and animals, affecting endothelial function. However, studies concerning… (More)
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2008
2008
Role of oxidant stress on AT1 receptor expression in neurons of rabbits with heart failure and in cultured neurons.
We have previously reported that the expression of Angiotensin II (Ang II) type 1 receptors (AT1R) was increased in the rostral… (More)
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2004
2004
Central Tempol alters basal sympathetic nerve discharge and attenuates sympathetic excitation to central ANG II.
In the present study, we established dose-response relationships between central administration of 4-hydroxy-2,2,6,6… (More)
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2003
2003
Tempol-H inhibits opacification of lenses in organ culture.
Cataract is the world's leading cause of blindness and a disease for which no efficacious medical therapy is available. To screen… (More)
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Highly Cited
2001
Highly Cited
2001
Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity.
Although arsenic is a well-established human carcinogen, the mechanisms by which it induces cancer remain poorly understood. We… (More)
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Highly Cited
1992
Highly Cited
1992
Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide.
Dismutation of superoxide has been shown previously to be catalyzed by stable nitroxide compounds. In the present study, the… (More)
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