TCPOBOP

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Obesity and type 2 diabetes are related metabolic disorders of high prevalence. The constitutive androstane receptor (CAR) was… (More)
Is this relevant?
2007
2007
AIM To ascertain whether constitutive androstane receptor (CAR) activation by 1,4-bis-[2-(3,5,-dichloropyridyloxy)] benzene… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The multidrug resistance-associated proteins (Mrp) are ATP-dependent transporters that export a variety of conjugated and… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The nuclear receptors CAR and PXR activate hepatic genes in response to therapeutic drugs and xenobiotics, leading to the… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The orphan nuclear receptor CAR (NR1I3) has been characterized as a central component in the coordinate response to xenobiotic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The nuclear receptors, farnesoid X receptor (FXR) and pregnane X receptor (PXR), are important in maintaining bile acid… (More)
Is this relevant?
2003
2003
The nuclear receptor Constitutive Androstane Receptor (CAR) binds DNA as a heterodimer with the retinoic-X receptor and activates… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The products of the cytochrome P450 (CYP) genes play an important role in the detoxification of xenobiotics and environmental… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Organisms encounter a wide range of foreign compounds—or ‘xenobiotics’—with potentially harmful consequences. The cytochrome P450… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
A wide range of xenobiotic compounds are metabolized by cytochrome P450 (CYP) enzymes, and the genes that encode these enzymes… (More)
Is this relevant?