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TCN2 gene

Known as: macrocytic anemia, VITAMIN B12-BINDING PROTEIN 2, D22S750 
National Institutes of Health

Related topics

Related topics

3 relations
Anemia, MacrocyticTranscobalamin IITranscobalamin II deficiency

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Environmental influence on the worldwide prevalence of a 776C→G variant in the transcobalamin gene (TCN2)
Background: A 776C→G variant (dbSNP ID: rs1801198) in the transcobalamin gene (TCN2; MIM# 275350) decreases the cellular and… 
1998
1998
A 69-Base Pair Fragment Derived from Human Transcobalamin II Promoter Is Sufficient for High Bidirectional Activity in the Absence of a TATA Box and an Initiator Element in Transfected Cells
A 69-base pair (bp) (−581/−513) fragment derived from human transcobalamin II distal promoter constructed upstream of a… 
1995
1995
Membrane Expression and Interactions of Human Transcobalamin II Receptor (*)
Antiserum raised to purified 62-kDa human placental transcobalamin II receptor (TC II-R) has been used to study its synthesis and… 
Highly Cited
1991
Highly Cited
1991
The cDNA sequence and the deduced amino acid sequence of human transcobalamin II show homology with rat intrinsic factor and human transcobalamin I.
The cellular uptake of cobalamin (Cbl, vitamin B12) is mediated by transcobalamin II (TCII), a plasma protein that binds Cbl and… 
Highly Cited
1990
Highly Cited
1990
Expression of transcobalamin II receptors by human leukemia K562 and HL-60 cells.
Plasma membrane receptors for the serum cobalamin-binding protein transcobalamin II (TCII) were identified on human leukemia K562… 
Review
1985
Review
1985
lambda -shaped ultrasound-attenuation peak in superconducting (U,Th)Be13.
VOLUME 55, NUMBER 12 A, PHYSICAL REVIEW LETTERS 16 SEPTEMBER 1985 Peak in Suyerconducting -Shayed Ultrasound-Attenuation (U, Th… 
Highly Cited
1979
Highly Cited
1979
Megaloblastic anemia as a result of an abnormal transcobalamin II (Cardeza).
A 34-year-old Black woman had severe megaloblastic anemia in childhood. Initially, and over the years, she responded well to… 
Review
1978
Review
1978
Detection of genetic variation with radioactive ligands. III. genetic polymorphism of transcobalamin II in human plasma.
We detected genetically determined, electrophoretic variants of vitamin B12 binding proteins, most probably transcobalamin II, in… 
1976
1976
Increased circulating levels of transcobalamin ii in gaucher's disease.
The presence of several serum protein abnormalities in Gaucher's disease prompted a study of vitamin B12 binding proteins, in… 
1976
1976
Biosynthesis of transcobalamin II by adult rat liver parenchymal cells in culture.
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