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TCF3/PBX1 Fusion Gene

Known as: PBX1/E2A FUSION GENE, E2A/PBX1 Fusion Gene, TCF3-PBX1 Fusion Gene 
A fusion gene that results from a chromosomal translocation t(1;19)(q23;p13) which fuses intron 13 of the TCF3 gene with exon 2 of the PBX1 gene… 
National Institutes of Health

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2 relations
E2A-Pbx1 fusion proteinTranscriptional Activation

Papers overview

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2015
2015
Detection and analysis of tumour biomarkers to strengthen the diagnosis of acute and chronic leukaemias
2015
2015
Abstract B07: Prevalence of the most common fusion gene transcripts in 1080 Egyptian pediatric acute lymphoblastic leukemia patients: Children Cancer Hospital Egypt (CCHE) experience.
Introduction: Childhood acute lymphoblastic leukemia (ALL) is a highly heterogeneous disease with distinct biological subgroups… 
Review
2014
Review
2014
Novel mechanisms of transcriptional regulation by leukemia fusion proteins
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2013
2013
Characteristics of the four subtypes of myelodysplastic/myeloproliferative neoplasms
The aim of the present study was to investigate the characteristics of the four subtypes of myelodysplastic/myeloproliferative… 
2011
2011
Real-time qPCR for assessment of minimal residual disease in acute myeloid and lymphoid leukemia Metodă real-time qPCR pentru evaluarea bolii minime reziduale în leucemiile acute mieloide şi limfoide
Evaluation of minimal residual disease is of major importance in the course of acute leukemia treatment. There are a number of… 
Review
2009
Review
2009
[Acute T cells lymphoblastic leukemia with a t(1;19)(q23;p13) and E2A-PBX1 in an adult: one case report and literature review].
OBJECTIVE To report a case of T cell acute lymphoblastic leukemia (ALL) with t(1;19)(q23;pl3) and E2A-PBX1 fusion gene, which is… 
2008
2008
[Correlation of E2a-pbx1 expression level with clinical characteristics and early response to treatment in children with acute lymphoblastic leukemia].
This study purposed to investigate the correlation of expression level of e2a-pbx1 (immunoglobulin enhancer binding factor-Pre-B… 
2008
2008
Comparison of the biology of Down syndrome (DS) acute lymphoblastic leukemia (ALL) and non-DS ALL: Children's Oncology Group (COG) study P9900
10003 Background: DS ALL is a heterogeneous disorder with inferior survival compared to non-DS. Controversy exists regarding the… 
Highly Cited
2001
Highly Cited
2001
HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation
HoxB8 was the first homeobox gene identified as a cause of leukemia. In murine WEHI3B acute myeloid leukemia (AML) cells… 
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