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TBC1D4 gene

Known as: TBC1D4, AKT SUBSTRATE, 160-KD, KIAA0603 
National Institutes of Health

Related topics

Related topics

3 relations
TBC1D10A geneTBC1D3 geneTBC1D5 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Challenging of AS160/TBC1D4 Alters Intracellular Lipid milieu in L6 Myotubes Incubated With Palmitate
The Akt substrate of 160 kDa (AS160) is a key regulator of GLUT4 translocation from intracellular depots to the plasma membrane… 
Highly Cited
2013
Highly Cited
2013
Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs
RAB10 and RAB14 function at sequential steps of insulin-stimulated GLUT4 translocation to the plasma membrane. RAB14 functions… 
2013
2013
Telmisartan Improves Insulin Resistance of Skeletal Muscle Through Peroxisome Proliferator–Activated Receptor-δ Activation
The mechanisms of the improvement of glucose homeostasis through angiotensin receptor blockers are not fully elucidated in… 
2011
2011
Loss of AS160 Akt Substrate Causes Glut4 Protein to Accumulate in Compartments That Are Primed for Fusion in Basal Adipocytes*
The Akt substrate AS160 (TCB1D4) regulates Glut4 exocytosis; shRNA knockdown of AS160 increases surface Glut4 in basal adipocytes… 
2011
2011
Conditioned medium from hypoxia-treated adipocytes renders muscle cells insulin resistant.
2011
2011
Emerging role of Akt substrate protein AS160 in the regulation of AQP2 translocation.
AS160, a novel Akt substrate of 160 kDa, contains a Rab GTPase-activating protein (GAP) domain. The present study examined the… 
Highly Cited
2009
Highly Cited
2009
Inhibition of Contraction-Stimulated AMP-Activated Protein Kinase Inhibits Contraction-Stimulated Increases in PAS-TBC1D1 and Glucose Transport Without Altering PAS-AS160 in Rat Skeletal Muscle
OBJECTIVE Phosphorylation of two members of the TBC1 domain family of proteins, Akt substrate of 160 kDa (AS160, also known as… 
Highly Cited
2008
Highly Cited
2008
Direct Quantification of Fusion Rate Reveals a Distal Role for AS160 in Insulin-stimulated Fusion of GLUT4 Storage Vesicles*
Insulin-stimulated GLUT4 translocation to the plasma membrane constitutes a key process for blood glucose control. However… 
Highly Cited
2008
Highly Cited
2008
The effect of exercise and insulin on AS160 phosphorylation and 14-3-3 binding capacity in human skeletal muscle.
AS160 is an Akt substrate of 160 kDa implicated in the regulation of both insulin- and contraction-mediated GLUT4 translocation… 
2007
2007
Resistance Exercise and Insulin Regulate AS160 and Interaction With 14-3-3 in Human Skeletal Muscle
A single bout of aerobic exercise can enhance insulin action, but whether a similar effect occurs after resistance exercise is… 
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