TBC1D4 gene

Known as: TBC1D4, AKT SUBSTRATE, 160-KD, KIAA0603 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Background:The activity of the protein kinase Akt is frequently dysregulated in cancer and is an important factor in the growth… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE Rictor is an essential component of mammalian target of rapamycin (mTOR) complex (mTORC) 2, a kinase that… (More)
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2009
2009
OBJECTIVE Phosphorylation of two members of the TBC1 domain family of proteins, Akt substrate of 160 kDa (AS160, also known as… (More)
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Highly Cited
2008
Highly Cited
2008
Rictor is an essential component of mTOR (mammalian target of rapamycin) complex 2 (mTORC2), a kinase complex that phosphorylates… (More)
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Highly Cited
2008
Highly Cited
2008
Protein kinase B (PKB)/Akt has been strongly implicated in the insulin-dependent stimulation of GLUT4 translocation and glucose… (More)
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2007
2007
We examined, in soleus muscle, the effects of prolonged palmitate exposure (0, 6, 12, 18 h) on insulin-stimulated glucose… (More)
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Highly Cited
2006
Highly Cited
2006
Translocation of the insulin-regulated glucose transporter GLUT4 to the cell surface is dependent on the phosphatidylinositol 3… (More)
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Highly Cited
2005
Highly Cited
2005
AS160 is a newly described substrate for the protein kinase Akt that links insulin signaling and GLUT4 trafficking. In this study… (More)
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Highly Cited
2004
Highly Cited
2004
Insulin maintains whole body blood glucose homeostasis, in part, by regulating the amount of the GLUT4 glucose transporter on the… (More)
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Highly Cited
2003
Highly Cited
2003
Insulin stimulates the rapid translocation of intracellular glucose transporters of the GLUT4 isotype to the plasma membrane in… (More)
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