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TBC 3486

Known as: TBC-3486, TBC3486 
National Institutes of Health

Papers overview

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2016
2016
AVA4746, an Orally Available, Clinical Grade Antagonist of Integrin Alpha 4, Sensitizes Pre-B Cell Acute Lymphoblastic Leukemia to Chemotherapy
Background. Even though remarkable progress has been made in the treatment of childhood acute lymphoblastic leukemia (ALL… 
2010
2010
Potent in vivo suppression of inflammation by selectively targeting the high affinity conformation of integrin α4β1.
2002
2002
A 3D structure model of integrin alpha 4 beta 1 complex: I. Construction of a homology model of beta 1 and ligand binding analysis.
It is well established that integrin alpha 4 beta 1 binds to the vascular cell adhesion molecule (VCAM) and fibronectin and plays… 
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