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TAP complex

Known as: TAP complex location, transporter associated with antigen presentation 
A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic… Expand
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
In most mammals, the MHC class I molecules are polymorphic and determine the specificity of peptide presentation, whereas the… Expand
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Highly Cited
2008
Highly Cited
2008
The basis for strong immunogenetic associations between particular human leukocyte antigen (HLA) class I allotypes and… Expand
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Highly Cited
2001
Highly Cited
2001
Oncolytic herpes simplex virus type 1 (HSV-1) vectors are promising therapeutic agents for cancer. Their efficacy depends on the… Expand
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Highly Cited
2000
Highly Cited
2000
Bone marrow–derived antigen-presenting cells (APCs) take up cell-associated antigens and present them in the context of major… Expand
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Highly Cited
1998
Highly Cited
1998
The herpes simplex virus (HSV) infected cell protein (ICP)47 blocks CD8+ T cell recognition of infected cells by inhibiting the… Expand
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Highly Cited
1998
Highly Cited
1998
ABSTRACT Herpes simplex virus serotype 1 (HSV-1) expresses an immediate-early protein, ICP47, that effectively blocks the major… Expand
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Highly Cited
1997
Highly Cited
1997
BALB/c mice vaccinated with vaccinia virus expressing the major surface glycoprotein G of respiratory syncytial virus (RSV… Expand
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Highly Cited
1996
Highly Cited
1996
The herpes simplex virus (HSV) ICP47 protein inhibits the MHC class I antigen presentation pathway by inhibiting the transporter… Expand
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Highly Cited
1995
Highly Cited
1995
The development of cervical carcinoma is strongly associated with specific types of human papillomaviruses (HPVs). A role for… Expand
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Highly Cited
1994
Highly Cited
1994
Malignant tumor cells can escape CD8+ cytotoxic T cell killing by downregulating class I major histocompatibility complex (MHC… Expand
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