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TAP complex

Known as: TAP complex location, transporter associated with antigen presentation 
A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Detection of TAP family dimerizations by an in vivo assay in mammalian cells.
The transporter associated with antigen presentation (TAP) is an ATP-binding cassette (ABC) protein which transports peptides for… 
Review
2004
Review
2004
Proteomics in cancer cell research: an analysis of therapy resistance.
Highly Cited
2003
Highly Cited
2003
Immunization with tumor‐derived ER chaperone grp170 elicits tumor‐specific CD8+ T‐cell responses and reduces pulmonary metastatic disease
Glucose‐regulated protein (grp) 170 is a molecular chaperone localized in endoplasmic reticulum (ER), which has been demonstrated… 
Highly Cited
2003
Highly Cited
2003
Enhancing major histocompatibility complex class I antigen presentation by targeting antigen to centrosomes.
Several strategies that increase proteasomal degradation of antigen have been shown to improve MHC class I presentation of… 
2002
2002
Transduction of dendritic cells by antigen-encoding lentiviral vectors permits antigen processing and MHC class I-dependent presentation.
BACKGROUND Because antigen-presenting dendritic cells (DCs) play a major role in the polarization of T cells, including T(H)2… 
2001
2001
A measles virus glycoprotein-derived human CTL epitope is abundantly presented via the proteasomal-dependent MHC class I processing pathway.
Peptides derived from measles virus (MV) are presented by MHC class I molecules at widely divergent levels, but it is currently… 
2001
2001
Reduced expression of TAP-1 and TAP-2 in posterior uveal melanoma is associated with progression to metastatic disease
In order to determine the effects of the loss or reduced expression of molecules associated with antigen presentation… 
Highly Cited
1998
Highly Cited
1998
Herpes Simplex Virus Type 2 ICP47 Inhibits Human TAP but Not Mouse TAP
ABSTRACT Herpes simplex virus serotype 1 (HSV-1) expresses an immediate-early protein, ICP47, that effectively blocks the major… 
Highly Cited
1998
Highly Cited
1998
Induction of primary, human antigen-specific cytotoxic T lymphocytes in vitro using dendritic cells pulsed with peptides.
Using a murine metastasis model, we have previously shown that antigen-presenting cells (APC) loaded with unfractionated peptides… 
1997
1997
An improved assembly assay for peptide binding to HLA-B*2705 and H-2K(k) class I MHC molecules.
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