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TAP complex

Known as: TAP complex location, transporter associated with antigen presentation 
A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
BackgroundMany processes in molecular biology involve the recognition of short sequences of nucleic-or amino acids, such as the… 
Highly Cited
2001
Highly Cited
2001
Oncolytic herpes simplex virus type 1 (HSV-1) vectors are promising therapeutic agents for cancer. Their efficacy depends on the… 
Highly Cited
2000
Highly Cited
2000
Bone marrow–derived antigen-presenting cells (APCs) take up cell-associated antigens and present them in the context of major… 
Highly Cited
1998
Highly Cited
1998
ABSTRACT Herpes simplex virus serotype 1 (HSV-1) expresses an immediate-early protein, ICP47, that effectively blocks the major… 
Highly Cited
1998
Highly Cited
1998
The herpes simplex virus (HSV) infected cell protein (ICP)47 blocks CD8+ T cell recognition of infected cells by inhibiting the… 
Highly Cited
1997
Highly Cited
1997
Several recent studies have shown that dendritic cells (DC) pulsed with soluble proteins can present peptide epitopes derived… 
Highly Cited
1996
Highly Cited
1996
The herpes simplex virus (HSV) ICP47 protein inhibits the MHC class I antigen presentation pathway by inhibiting the transporter… 
Highly Cited
1994
Highly Cited
1994
In previous studies we have shown down-regulation of class I major histocompatibility complex (MHC) expression in a significant… 
Highly Cited
1994
Highly Cited
1994
Malignant tumor cells can escape CD8+ cytotoxic T cell killing by downregulating class I major histocompatibility complex (MHC…