TAL1 wt Allele

Known as: SCL, T-Cell Acute Lymphocytic Leukemia 1 wt Allele, TCL5 
Human TAL1 wild-type allele is located in the vicinity of 1p32 and is approximately 15 kb in length. This allele, which encodes T-cell acute… (More)

Topic mentions per year

Topic mentions per year

1989-2016
012319892016

Papers overview

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2010
2010
The majority of long-term reconstituting hematopoietic stem cells (LT-HSCs) in the adult is in G(0), whereas a large proportion… (More)
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2009
2009
One of the principal issues facing biomedical research is to elucidate developmental pathways and to establish the fate of stem… (More)
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2003
2003
The Tal1 gene (also called Scl or TCL5) encodes a basic helix-loop-helix transcription factor required for hematopoiesis and… (More)
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2002
2002
The differentiation of neural progenitors into the many classes of neurons that exist in the mature spinal cord is a process that… (More)
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1993
1993
SCL (TAL-1) is implicated in the generation of human T-cell acute lymphoblastic leukaemia. To directly examine the role of this… (More)
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Highly Cited
1992
Highly Cited
1992
The SCL (tal-1, TCL5) gene is a member of the basic domain, helix-loop-helix (bHLH) class of putative transcription factors. We… (More)
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1992
1992
The SCL gene encodes a putative transcription factor with a basic helix-loop-helix (B-HLH) motif and is known to be predominantly… (More)
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1992
1992
Nearly 30 percent of patients with T-cell acute lymphoblastic leukemia (T-ALL) exhibit a tumor-specific rearrangement of the TAL1… (More)
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Highly Cited
1990
Highly Cited
1990
A fusion complementary DNA in the T cell line HSB-2 elucidates a provocative mechanism for the disruption of the putative… (More)
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Highly Cited
1989
Highly Cited
1989
We analyzed a t(1;14)(p32;q11) chromosomal translocation in a human lymphohemopoietic stem cell line derived from a patient with… (More)
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