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TAK-683

 
National Institutes of Health

Papers overview

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2018
2018
Abstract TAK‐448 and TAK‐683 are kisspeptin agonist analogs with improved in vivo stability and activity. Previous studies showed… Expand
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2017
2017
The present study aimed to evaluate hormonal responses and their association with the TAK-683 blood concentrations in goats… Expand
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2016
2016
Metastin/kisspeptin is an endogenous ligand of KISS1 Receptor (KISS1R). Metastin and KISS1R are suggested to play crucial roles… Expand
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2015
2015
This study aimed to evaluate the hormonal and ovarian responses to the administration of a metastin/kisspeptin analog (TAK-683… Expand
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2014
2014
This study evaluated the effects of follicular phase administration of TAK-683, an investigational metastin/kisspeptin analog, on… Expand
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2014
2014
The continuous activation of the kisspeptin receptor by its agonists causes the abrogation of kisspeptin signaling, leading to… Expand
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2014
2014
Kisspeptin/metastin, a hypothalamic peptide, plays a pivotal role in controlling gonadotropin-releasing hormone (GnRH) neurons… Expand
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2013
2013
Abstract The aim of the present study was to determine if the estradiol-induced luteinizing hormone (LH) surge is influenced by… Expand
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2013
2013
AIMS Two randomized, double-blind, placebo-controlled studies were performed to characterize the safety, tolerability… Expand
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2012
2012
TAK-448 and TAK-683, investigational agents with potential utility in the treatment of prostate cancer, are potent low molecular… Expand
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