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T 1095

Known as: 3-(Benzo(b)furan-5-yl)-2', 6'-dihydroxy-4'-methylpropiophenone-2'-O-(6-O-methoxycarbonyl)-beta-D- glucopyranoside, T-1095 
National Institutes of Health

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2 relations

Broader (2)

CarbonatesGlucosides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
USE AND PROCESS FOR THEIR MANUFACTURE
of JP2004359630. International Search Report for corresponding international applica tion PCT/EP2005/002618 mailed Jun. 30, 2005… 
2006
2006
Reduction of renal transport maximum for glucose by inhibition of NA(+)-glucose cotransporter suppresses blood glucose elevation in dogs.
T-1095, an orally active inhibitor of Na(+)-glucose cotransporter (SGLT), excretes excess plasma glucose into urine, lowers blood… 
Review
2004
Review
2004
Glucose transporter and Na+/glucose cotransporter as molecular targets of anti-diabetic drugs.
Glucose transporters, or membrane proteins, which incorporate glucose into the cell, can be divided into two groups: the… 
2004
2004
SGLT as a therapeutic target
The expression of the sodium/glucose cotransporter (SGLT), a membrane protein, is limited to renal tubules and the intestinal… 
2002
2002
Beneficial Effect Of T‐1095, A Selective Inhibitor Of Renal Na+–Glucose Cotransporters, On Metabolic Index And Insulin Secretion In Spontaneously Diabetic Gk Rats
1. To investigate the pharmacological effects of T‐1095, this novel derivative of phlorizin was administered to GK rats for 8… 
2002
2002
T-1095 promising in diabetes mellitus
  • 2002
  • Corpus ID: 195162290
2001
2001
T-1095: Antidiabetic sodium-glucose cotransporter inhibitor
Highly Cited
2000
Highly Cited
2000
Hyperglycemia contributes insulin resistance in hepatic and adipose tissue but not skeletal muscle of ZDF rats.
To determine the contribution of hyperglycemia to the insulin resistance in various insulin-sensitive tissues of Zucker diabetic… 
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