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Systemic onset juvenile chronic arthritis

Known as: Systemic Juvenile Idiopathic Arthritis, Juvenile RA, Systemic Onset, Systemic Onset Juvenile Idiopathic Arthritis 
A category of juvenile idiopathic arthritis defined by the presence of arthritis and high fevers, and accompanied by at least 2 of the following… 
National Institutes of Health

Related topics

Related topics

5 relations
Connective and Soft TissueJointsJuvenile arthritisJuvenile-Onset Still Disease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Drug Retention Rate and Predictive Factors of Drug Survival for Interleukin-1 Inhibitors in Systemic Juvenile Idiopathic Arthritis
Background and Objectives: Few studies have reported the drug retention rate (DRR) of biologic drugs in juvenile idiopathic… 
Highly Cited
2014
Highly Cited
2014
Clinical Features, Treatment, and Outcome of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A Multinational, Multicenter Study of 362 Patients
To describe the clinical, laboratory, and histopathologic features, current treatment, and outcome of patients with macrophage… 
Review
2014
Review
2014
The Biology and Medical Implications of Interleukin-6
Cytokines are soluble mediators, which aid cell-to-cell communication in immune responses, and interleukin-6 (IL-6) is a… 
Highly Cited
2014
Highly Cited
2014
Effectiveness of First‐Line Treatment With Recombinant Interleukin‐1 Receptor Antagonist in Steroid‐Naive Patients With New‐Onset Systemic Juvenile Idiopathic Arthritis: Results of a Prospective…
To conduct a prospective cohort study using anakinra, a recombinant IL‐1 receptor antagonist (IL‐1Ra), as first‐line therapy in… 
Review
2014
Review
2014
Review: Is There a Window of Opportunity for Treatment of Systemic Juvenile Idiopathic Arthritis?
Among subcategories of juvenile idiopathic arthritis (JIA), one stands out as very different from the others. Systemic JIA… 
Review
2012
Review
2012
Targeting Interleukin-6: All the Way to Treat Autoimmune and Inflammatory Diseases
Interleukin (IL)-6, a cytokine featuring redundancy and pleiotropic activity, contributes to host defense against acute… 
Highly Cited
2010
Highly Cited
2010
Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis.
OBJECTIVE Macrophage activation syndrome (MAS) in systemic onset juvenile idiopathic arthritis (SoJIA) is considered to be an… 
Highly Cited
2007
Highly Cited
2007
The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis.
OBJECTIVE Macrophage activation syndrome is characterized by an overwhelming inflammatory reaction driven by excessive expansion… 
Review
2000
Review
2000
Systemic onset juvenile idiopathic arthritis: a retrospective study of 80 consecutive patients followed for 10 years.
OBJECTIVE To investigate the relationships between systemic onset juvenile idiopathic arthritis disease activity, course of the… 
Highly Cited
1998
Highly Cited
1998
A possible role for soluble IL-6 receptor in the pathogenesis of systemic onset juvenile chronic arthritis.
Investigation of the agonist and two antagonists to interleukin 6 (IL-6) and their possible role in the pathogenesis of different… 
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