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Systemic Scleroderma

Known as: Systemic sclerosis, Diffuse Scleroderma, SSc, Diffuse Sclerosis 
A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The… 
National Institutes of Health

Related topics

Related topics

28 relations
AutoantibodiesCREST SyndromeChloroquineChloroquine hydrochloride

Narrower (2)

Juvenile-onset sclerodermarenal scleroderma

Broader (1)

Scleroderma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1997
Highly Cited
1997
In vivo CD30 expression in human diseases with predominant activation of Th2‐like T cells
CD3O is a member of the tumor necrosis factor (TNF) receptor family, originally described as a marker for Hodgkin and Reed… 
Highly Cited
1997
Highly Cited
1997
The concentrations and bioconcentration factors of mercury in mushrooms from the Mierzeja Wiślana sand-bar, northern Poland.
Highly Cited
1996
Highly Cited
1996
Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts. Increased proportion of high collagen-producing cells in systemic sclerosis fibroblasts.
OBJECTIVE The goal of this study was to quantitatively analyze the distribution of collagen synthesis in normal and systemic… 
Highly Cited
1995
Highly Cited
1995
Increased susceptibility to oxidation of low-density lipoproteins isolated from patients with systemic sclerosis.
OBJECTIVE To examine the resistance to oxidation of low-density lipoproteins (LDL) from patients with systemic sclerosis (SSc… 
Highly Cited
1994
Highly Cited
1994
Antihistone antibodies in systemic sclerosis. Association with pulmonary fibrosis.
OBJECTIVE To determine the prevalence and clinical significance of antihistone antibodies (AHA) in systemic sclerosis (SSc… 
Highly Cited
1994
Highly Cited
1994
Micronutrient antioxidant status in patients with primary Raynaud's phenomenon and systemic sclerosis.
OBJECTIVE To investigate the possibility that micronutrient antioxidant status is an important factor in determining the severity… 
Highly Cited
1991
Highly Cited
1991
Molecular characterization of an autoantigen of PM-Scl in the polymyositis/scleroderma overlap syndrome: a unique and complete human cDNA encoding an apparent 75-kD acidic protein of the nucleolar…
About 50% of patients with the polymyositis/scleroderma (PM-Scl) overlap syndrome are reported to have autoantibodies to a… 
Review
1978
Review
1978
Increased collagen accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma).
Abstract Fibroblast monolayers were established by explant culture of dermis from patients with PSS and from normal individuals… 
Highly Cited
1977
Highly Cited
1977
A study of releasable Ca fractions in smooth muscle cells of the rabbit aorta
The distribution of Ca in the cellular compartment of smooth muscle cells of the rabbit aorta has been studied by analyzing the… 
Highly Cited
1941
Highly Cited
1941
Is There a Common Denominator in Scleroderma, Dermatomyositis, Disseminated Lupus Erythematosus, the Libman-Sacks Syndrome and Polyarteritis Nodosa?
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