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Systemic Scleroderma

Known as: Systemic sclerosis, Diffuse Scleroderma, SSc, Diffuse Sclerosis 
A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The… 
National Institutes of Health

Related topics

Related topics

28 relations
AutoantibodiesCREST SyndromeChloroquineChloroquine hydrochloride

Narrower (2)

Juvenile-onset sclerodermarenal scleroderma

Broader (1)

Scleroderma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1991
1991
Systemic sclerosis (scleroderma)
Estimating prognosis in systemic sclerosis is particularly difficult for a number of reasons. First, it is a disorder of… 
Highly Cited
1986
Highly Cited
1986
B-mode ultrasound evaluation of skin thickness in progressive systemic sclerosis.
B-mode ultrasound scanning was studied as a noninvasive means of determining skin thickness in the extremities of patients with… 
Highly Cited
1985
Highly Cited
1985
Antikeratin antibodies in serum and synovial fluid show specificity for rheumatoid arthritis in a study of connective tissue diseases.
Tests for antikeratin antibodies (AKA) were performed on 2152 disease-associated and control sera by indirect immunofluorescence… 
Highly Cited
1983
Highly Cited
1983
Progressive systemic sclerosis (PSS, scleroderma) dermal fibroblasts synthesize increased amounts of glycosaminoglycan.
Fibroblast monolayers were established by explant culture of dermis from seven patients with early, rapidly advancing PSS… 
Highly Cited
1980
Highly Cited
1980
Collagen types synthesized in dermal fibroblast cultures from patients with early progressive systemic sclerosis.
Fibroblast cultures were established by explant culture from upper and lower dermis of 7 normal donors and 10 patients with early… 
Review
1978
Review
1978
Increased collagen accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma).
Abstract Fibroblast monolayers were established by explant culture of dermis from patients with PSS and from normal individuals… 
Review
1978
Review
1978
Control of hypertension and reversal of renal failure in scleroderma.
MALIGNANT hypertension and rapid deterioration in renal function often occur in systemic scleroderma. Since medical therapy of… 
Highly Cited
1976
Highly Cited
1976
Antibodies to components of extractable nuclear antigen. Clinical characteristics of patients.
Forty-four patients with antibodies to ribonuclease-sensitive extractable nuclear antigen (ENA), ribonuclease-resistant ENA, or… 
1960
1960
[The sulfuric acid esters of cerebron and kerasin as storage substances in leukodystrophy of the Scholz type (metachromatic form of diffuse sclerosis)].
1949
1949
POLIODYSTROPHIA CEREBRI PROGRESSIVA (INFANTILIS): Report of a Case
DURING the last thirty years, cases of hereditary disease have occurred in which the white matter of the brain was extensively…