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Systemic Scleroderma

Known as: Systemic sclerosis, Diffuse Scleroderma, SSc, Diffuse Sclerosis 
A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The… 
National Institutes of Health

Related topics

Related topics

28 relations
AutoantibodiesCREST SyndromeChloroquineChloroquine hydrochloride

Narrower (2)

Juvenile-onset sclerodermarenal scleroderma

Broader (1)

Scleroderma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Layer-by-layer coating of degradable microgels for pulsed drug delivery.
Highly Cited
2006
Highly Cited
2006
Surface modification of multiwalled carbon nanotubes via nitroxide‐mediated radical polymerization
The nitroxide-mediated radical polymerization of styrene was carried out on the surfaces of multiwalled carbon nanotubes (MWNTs… 
Highly Cited
1996
Highly Cited
1996
Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts. Increased proportion of high collagen-producing cells in systemic sclerosis fibroblasts.
OBJECTIVE The goal of this study was to quantitatively analyze the distribution of collagen synthesis in normal and systemic… 
Highly Cited
1994
Highly Cited
1994
Micronutrient antioxidant status in patients with primary Raynaud's phenomenon and systemic sclerosis.
OBJECTIVE To investigate the possibility that micronutrient antioxidant status is an important factor in determining the severity… 
Review
1992
Review
1992
A brief overview of the pathogenesis of scleroderma (systemic sclerosis).
Although definitive answers are not yet forthcoming, understanding the mechanisms of fibrosis in scleroderma might improve the… 
Highly Cited
1991
Highly Cited
1991
Elevated plasma levels of endothelin-1 in systemic sclerosis.
Highly Cited
1990
Highly Cited
1990
Dermal mast cell degranulation in systemic sclerosis.
Paired biopsy samples from involved and uninvolved skin were obtained from 19 patients with generalized scleroderma (11 with… 
Review
1978
Review
1978
Increased collagen accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma).
Abstract Fibroblast monolayers were established by explant culture of dermis from patients with PSS and from normal individuals… 
Highly Cited
1978
Highly Cited
1978
The kidney in progressive systemic sclerosis: a prospective study.
Nine normotensive progressive systemic sclerosis patients with normal renal function underwent renal biopsy. Four specimens had… 
Highly Cited
1941
Highly Cited
1941
Is There a Common Denominator in Scleroderma, Dermatomyositis, Disseminated Lupus Erythematosus, the Libman-Sacks Syndrome and Polyarteritis Nodosa?
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