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Systemic Scleroderma

Known as: Systemic sclerosis, Diffuse Scleroderma, SSc, Diffuse Sclerosis 
A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The… 
National Institutes of Health

Related topics

Related topics

28 relations
AutoantibodiesCREST SyndromeChloroquineChloroquine hydrochloride

Narrower (2)

Juvenile-onset sclerodermarenal scleroderma

Broader (1)

Scleroderma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Layer-by-layer coating of degradable microgels for pulsed drug delivery.
Highly Cited
2000
Highly Cited
2000
Increased numbers of microchimeric cells of fetal origin are associated with dermal fibrosis in mice following injection of vinyl chloride.
OBJECTIVE To develop a murine model for use in examining the role of microchimeric cells and certain chemical exposures in the… 
Highly Cited
1997
Highly Cited
1997
The concentrations and bioconcentration factors of mercury in mushrooms from the Mierzeja Wiślana sand-bar, northern Poland.
Highly Cited
1996
Highly Cited
1996
Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts. Increased proportion of high collagen-producing cells in systemic sclerosis fibroblasts.
OBJECTIVE The goal of this study was to quantitatively analyze the distribution of collagen synthesis in normal and systemic… 
Highly Cited
1994
Highly Cited
1994
Micronutrient antioxidant status in patients with primary Raynaud's phenomenon and systemic sclerosis.
OBJECTIVE To investigate the possibility that micronutrient antioxidant status is an important factor in determining the severity… 
Review
1978
Review
1978
Increased collagen accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma).
Abstract Fibroblast monolayers were established by explant culture of dermis from patients with PSS and from normal individuals… 
Highly Cited
1977
Highly Cited
1977
A study of releasable Ca fractions in smooth muscle cells of the rabbit aorta
The distribution of Ca in the cellular compartment of smooth muscle cells of the rabbit aorta has been studied by analyzing the… 
Highly Cited
1957
Highly Cited
1957
Scleroderma in goldminers on the Witwatersrand with particular reference to pulmonary manifestations.
  • E. Ld
  • 1957
  • Corpus ID: 222498997
Highly Cited
1945
Highly Cited
1945
Pathology of Scleroderma, with Special Reference to the Changes in the Gastrointestinal Tract.
ascites; edema of feet; diffuse glomerular and arterial lesions of the kidneys; muscular atrophy of the gastrointestinal tract… 
Highly Cited
1941
Highly Cited
1941
Is There a Common Denominator in Scleroderma, Dermatomyositis, Disseminated Lupus Erythematosus, the Libman-Sacks Syndrome and Polyarteritis Nodosa?
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