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Systemic Scleroderma

Known as: Systemic sclerosis, Diffuse Scleroderma, SSc, Diffuse Sclerosis 
A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The… 
National Institutes of Health

Related topics

Related topics

28 relations
AutoantibodiesCREST SyndromeChloroquineChloroquine hydrochloride

Narrower (2)

Juvenile-onset sclerodermarenal scleroderma

Broader (1)

Scleroderma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Layer-by-layer coating of degradable microgels for pulsed drug delivery.
Highly Cited
2006
Highly Cited
2006
Surface modification of multiwalled carbon nanotubes via nitroxide‐mediated radical polymerization
The nitroxide-mediated radical polymerization of styrene was carried out on the surfaces of multiwalled carbon nanotubes (MWNTs… 
Review
1995
Review
1995
Regulation of connective tissue synthesis in systemic sclerosis.
Excessive connective tissue deposition in the skin and other organs is the pathologic hallmark of systemic sclerosis (SSc), and… 
Highly Cited
1994
Highly Cited
1994
Micronutrient antioxidant status in patients with primary Raynaud's phenomenon and systemic sclerosis.
OBJECTIVE To investigate the possibility that micronutrient antioxidant status is an important factor in determining the severity… 
Review
1993
Review
1993
Autoantibodies in Scleroderma
  • M. Fritzler
  • Journal of dermatology (Print)
  • 1993
  • Corpus ID: 924958
Autoantibodies directed against nuclear, nucleolar, and a number of cytoplasmic components are described in the sera of… 
Review
1992
Review
1992
A brief overview of the pathogenesis of scleroderma (systemic sclerosis).
Although definitive answers are not yet forthcoming, understanding the mechanisms of fibrosis in scleroderma might improve the… 
Highly Cited
1983
Highly Cited
1983
Antibodies to SM and RNP
The charts of 150 consecutive patients found to have antibodies to Sm, ribonucleoprotein (RNP), or both were examined to… 
Review
1980
Review
1980
A histologic evaluation of mixed connective tissue disease in childhood.
Review
1978
Review
1978
Increased collagen accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma).
Abstract Fibroblast monolayers were established by explant culture of dermis from patients with PSS and from normal individuals… 
Highly Cited
1978
Highly Cited
1978
The kidney in progressive systemic sclerosis: a prospective study.
Nine normotensive progressive systemic sclerosis patients with normal renal function underwent renal biopsy. Four specimens had… 
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