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Sulpiride

Known as: Sulpiridum, N-((1-Ethyl-2-Pyrrolidinyl)Methyl)-5-Sulfamoyl-O-Anisamide, 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide 
A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index… 
National Institutes of Health

Related topics

Related topics

27 relations
Alprazolam / SulpirideIn BloodSulpiride:MCnc:Pt:Ser/Plas:Qnagonists

Broader (6)

Antidepressive AgentsAntidepressive Agents, Second-GenerationAntiemeticsAntipsychotic Agents

Narrower (12)

DeponertonDogmatilEglonylRIV 2093

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
On the metabolic origin of cancer: substances that target tumor metabolism
Work from our group and others clearly suggest the key role of altered metabolism in cancer. The goal of this review is to… 
1985
1985
Substituted benzamides with conformationally restricted side chains. 1. Quinolizidine derivatives as selective gastric prokinetic agents.
The gastric prokinetic action of metoclopramide may not be primarily due to its dopamine antagonist activity. The present aim was… 
1984
1984
Mechanism of phorbol myristate acetate-induced lymphotoxin production by a human T cell hybridoma.
Various hydroxyl radical scavengers markedly inhibited phorbol myristate acetate (PMA)-induced lymphotoxin (LT) production by a… 
1980
1980
Dopamine receptor blocking activity of sulpiride in the canine exocrine pancreas.
The inhibitory effect of sulpiride on dopamine receptors was investigated in the exocrine pancreas of dogs anesthetized with… 
1979
1979
Treatment of duodenal ulcer with antacid and sulpiride. A double-blind controlled study.
The effect of aluminum-magnesium hydroxide tablets (800 mg seven times per day) and that of sulpiride, a hypothalamic neurolaptic… 
Highly Cited
1977
Highly Cited
1977
An evaluation of a unique new antipsychotic agent, sulpiride: effects on serum prolactin and growth hormone levels.
Sulpiride is a new and chemically different neuroleptic. In a study of 16 severely ill schizophrenic patients, this compound… 
1977
1977
Effect of sulpiride on serum growth hormone and prolactin concentrations following L-DOPA administration in man.
The effect of chronic administration of sulpiride on serum human growth hormone (hGH), prolactin and thyroid stimulating hormone… 
Highly Cited
1976
Highly Cited
1976
Influence of dopaminergic agonists and antagonists on serum prolactin concentrations in the rat.
Inhibitors of dopaminergic neurotransmission, such as reserpine (RES), given alone or combined with alpha-methyl-p-tyrosine… 
1976
1976
Effect of sulpiride on plasma prolactin in rats.
I.v. injection of sulpiride (S; 0.5-20 mug/100 g b.w.) caused a significant and dose-related increase in plasma prolactin (Prl… 
1975
1975
Stimulation of human prolactin secretion by sulpiride.
Intramuscular injection of 100 mg of sulpiride significantly raised plasma human prolactin (hPRL) levels in all of 7 normal…