Sulpiride

Known as: Sulpiridum, N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-O-anisamide, 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide 
A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index… (More)

Topic mentions per year

Topic mentions per year

1967-2017
05010015019672017

Papers overview

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Highly Cited
2008
Highly Cited
2008
Cortical GABAergic dysfunction, a hallmark of both schizophrenia (SZ) and bipolar (BP) disorder pathophysiologies may relate to… (More)
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Highly Cited
2007
Highly Cited
2007
Brain anatomical networks are sparse, complex, and have economical small-world properties. We investigated the efficiency and… (More)
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Highly Cited
2004
Highly Cited
2004
Dopamine (DA) D2 receptor antagonists have been shown to produce similar impairments to those seen in Parkinson’s disease. These… (More)
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Highly Cited
2000
Highly Cited
2000
The role in spatial divided and sustained attention of D1 and D2-like dopamine (DA) receptors in the rat prelimbic medial… (More)
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Highly Cited
1999
Highly Cited
1999
Rationale: The mesotelencephalic dopamine system has been implicated in cognitive processes dependent on an intact prefrontal… (More)
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Highly Cited
1998
Highly Cited
1998
Dopamine (DA) within the prefrontal cortex (PFC) plays an important role in modulating the short-term retention of information… (More)
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Highly Cited
1992
Highly Cited
1992
The effect of tetanic activation of corticostriatal glutamatergic fibers was studied in striatal slices by utilizing… (More)
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Highly Cited
1992
Highly Cited
1992
Positron emission tomography and selective radioligands were used to determine D1 and D2 dopamine receptor occupancy induced by… (More)
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Highly Cited
1983
Highly Cited
1983
Extracellular single unit recording techniques were used to study the effects of both acute and repeated oral neuroleptic… (More)
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1975
1975
The cataleptic and antistereotypic abilities of clozapine, sulpiride and thioridazine were determined in the rat and compared… (More)
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