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Sulpiride

Known as: Sulpiridum, N-((1-Ethyl-2-Pyrrolidinyl)Methyl)-5-Sulfamoyl-O-Anisamide, 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide 
A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Cortical GABAergic dysfunction, a hallmark of both schizophrenia (SZ) and bipolar (BP) disorder pathophysiologies may relate to… Expand
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Highly Cited
2007
Highly Cited
2007
Brain anatomical networks are sparse, complex, and have economical small-world properties. We investigated the efficiency and… Expand
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Highly Cited
2000
Highly Cited
2000
Schizophrenia is a major therapeutic challenge of modern medicine, and one of the last frontiers of brain research. The illness… Expand
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Highly Cited
2000
Highly Cited
2000
The role in spatial divided and sustained attention of D1 and D2-like dopamine (DA) receptors in the rat prelimbic medial… Expand
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Highly Cited
1999
Highly Cited
1999
Abstract  Rationale: The mesotelencephalic dopamine system has been implicated in cognitive processes dependent on an intact… Expand
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Highly Cited
1998
Highly Cited
1998
Dopamine (DA) within the prefrontal cortex (PFC) plays an important role in modulating the short-term retention of information… Expand
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Highly Cited
1995
Highly Cited
1995
Reaction conditions for conjugation of two fluorescent ortho-substituted aniline derivatives, 2-amino benzamide (2-AB) and 2… Expand
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Highly Cited
1992
Highly Cited
1992
Positron emission tomography and selective radioligands were used to determine D1 and D2 dopamine receptor occupancy induced by… Expand
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Highly Cited
1992
Highly Cited
1992
1. Intracellular recordings were made from 241 ventral tegmental neurones in slices of rat midbrain. Seventy-seven per cent of… Expand
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Highly Cited
1992
Highly Cited
1992
The effect of tetanic activation of corticostriatal glutamatergic fibers was studied in striatal slices by utilizing… Expand
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