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Suicide Gene Therapy

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2011-2017
012320112017

Papers overview

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Review
2016
Review
2016
Cancer suicide gene therapy: a patent review.
INTRODUCTION Cancer is considered the second leading cause of death worldwide despite the progress made in early detection and… (More)
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Review
2016
Review
2016
Bacterial Toxins for Oncoleaking Suicidal Cancer Gene Therapy.
For suicide gene therapy, initially prodrug-converting enzymes (gene-directed enzyme-producing therapy, GDEPT) were employed to… (More)
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2015
2015
Redesigned Escherichia coli cytosine deaminase: a new facet of suicide gene therapy.
BACKGROUND The Escherichia coli cytosine deaminase (CD)/5-fluorocytosine (5-FC) approach emerges as a potential aid for suicide… (More)
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2015
2015
Editorial: Improving the safety of cell therapy products by suicide gene transfer
1 Institut National de la Santé et de la Recherche Médicale UMR 1098, Etablissement Français du Sang Bourgogne/Franche-Comt… (More)
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2014
2014
Complete regression of glioblastoma by mesenchymal stem cells mediated prodrug gene therapy simulating clinical therapeutic scenario.
Suicide gene therapy mediated by mesenchymal stem cells with their ability to engraft into tumors makes these therapeutic stem… (More)
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2014
2014
Safety and Efficacy of Suicide Gene Therapy with Adenosine Deaminase 5-Fluorocytosine Silmutaneously in in Vitro Cultures of Melanoma and Retinal Cell Lines
Local treatment as a treatment modality is gaining increased general acceptance over time. Novel drugs and methodologies of local… (More)
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Review
2014
Review
2014
Stem cells' guided gene therapy of cancer: New frontier in personalized and targeted therapy.
INTRODUCTION Diagnosis and therapy of cancer remain to be the greatest challenges for all physicians working in clinical oncology… (More)
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2013
2013
Suicide Gene Therapy for Cancer - Current Strategies.
Current cancer treatments may create profound iatrogenic outcomes. The adverse effects of these treatments still remain, as the… (More)
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2013
2013
Evaluation of miR-122-regulated suicide gene therapy for hepatocellular carcinoma in an orthotopic mouse model.
OBJECTIVE Intratumoral administration of adenoviral vector encoding herpes simplex virus (HSV) thymidine kinase (TK) gene (Ad-TK… (More)
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2011
2011
Suicide Gene Therapy to Increase the Safety of Chimeric Antigen Receptor-Redirected T Lymphocytes
Chimeric antigen receptors (CARs) are generated by fusing the antigen-binding motif of a monoclonal antibody (mAb) with the… (More)
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