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Suicide Gene Therapy

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Cancer is a devastating disease characterized by uncontrolled and aggressive cell growth. Suicide gene therapy (SGT) facilitating… Expand
2017
2017
Conventional anticancer agents are associated with limited therapeutic efficacy and substantial nonspecific cytotoxicity. Thus… Expand
2015
2015
The Escherichia coli cytosine deaminase (CD)/5‐fluorocytosine (5‐FC) approach emerges as a potential aid for suicide gene therapy… Expand
Highly Cited
2014
Highly Cited
2014
Suicide gene therapy mediated by mesenchymal stem cells with their ability to engraft into tumors makes these therapeutic stem… Expand
2014
2014
Suicide gene therapy (SGT) is a promising strategy for treating cancer. In this work, we show that thymidine phosphorylase (TP… Expand
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2014
2014
In an aggressive B16-F10 murine melanoma model, we evaluated the effectiveness and antitumor mechanisms triggered by a surgery… Expand
2014
2014
Local treatment as a treatment modality is gaining increased general acceptance over time. Novel drugs and methodologies of local… Expand
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2013
2013
OBJECTIVE Intratumoral administration of adenoviral vector encoding herpes simplex virus (HSV) thymidine kinase (TK) gene (Ad-TK… Expand
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2011
2011
Chimeric antigen receptors (CARs) are generated by fusing the antigen-binding motif of a monoclonal antibody (mAb) with the… Expand
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Highly Cited
2003
Highly Cited
2003
Our laboratory has employed replication-defective herpes simplex virus type 1 gene transfer vectors for treatment of animal… Expand