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Suicide Gene Therapy

 
National Institutes of Health

Papers overview

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2019
2019
Cancer is a devastating disease characterized by uncontrolled and aggressive cell growth. Suicide gene therapy (SGT) facilitating… Expand
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2017
2017
Conventional anticancer agents are associated with limited therapeutic efficacy and substantial nonspecific cytotoxicity. Thus… Expand
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2015
2015
BACKGROUND The Escherichia coli cytosine deaminase (CD)/5-fluorocytosine (5-FC) approach emerges as a potential aid for suicide… Expand
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2014
2014
Suicide gene therapy mediated by mesenchymal stem cells with their ability to engraft into tumors makes these therapeutic stem… Expand
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2014
2014
In an aggressive B16-F10 murine melanoma model, we evaluated the effectiveness and antitumor mechanisms triggered by a surgery… Expand
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2014
2014
Local treatment as a treatment modality is gaining increased general acceptance over time. Novel drugs and methodologies of local… Expand
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2013
2013
OBJECTIVE Intratumoral administration of adenoviral vector encoding herpes simplex virus (HSV) thymidine kinase (TK) gene (Ad-TK… Expand
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2011
2011
Chimeric antigen receptors (CARs) are generated by fusing the antigen-binding motif of a monoclonal antibody (mAb) with the… Expand
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2011
2011
The systemic delivery of gene therapeutics by non-viral methods has proven difficult. Transfection systems that are performing… Expand
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2003
2003
Our laboratory has employed replication-defective herpes simplex virus type 1 gene transfer vectors for treatment of animal… Expand
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