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Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS): current literature review.
TLDR
It is crucial to define asthma, COPD and overlap syndrome (ACOS), as notable clinical entities, which they share common pathologic and functional features, but they are characterized from differences in lung function, acute exacerbations, quality of life, hospital impact and mortality.
Treatment of non-small cell lung cancer (NSCLC).
TLDR
In advanced stage IIIB/IV or inoperable NSCLC pts, a multidisciplinary treatment should be offered consisted of 4 cycles of cisplatin-based chemotherapy plus a 3(rd) generation cytotoxic agent or a cytostatic drug.
Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled,
TLDR
The primary endpoint was disease-free survival in the overall population, the no-chemotherapy population, and patients with a potentially predictive gene signature, which could not identify a gene signature predictive of clinical benefit to MAGE-A3 immunotherapeutic.
Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases
TLDR
This class of antibiotics is efficacious with respect to controlling exacerbations of underlying respiratory problems, such as cystic fibrosis, asthma, bronchiectasis, panbrochiolitis and cryptogenic organising pneumonia.
Extrapelvic endometriosis: a rare entity or an under diagnosed condition?
TLDR
The multipotent localization of endometriosis in combination with the wide range of its clinical expression should raise the clinical suspicion in every woman with periodic symptoms of extrapelvic organs.
Pneumothorax after transthoracic needle biopsy of lung lesions under CT guidance.
TLDR
Although transthoracic needle biopsy is a widely accepted procedure with relatively few complications, precise planning and detailed knowledge of various aspects of the biopsy procedure is mandatory to avert complications.
Inhaled chemotherapy in lung cancer: future concept of nanomedicine
TLDR
An extensive review of drug delivery systems, pharmaceuticals, patient monitoring, methods of enhancing inhaled drug deposition, safety and efficacy, and also additional applications of inhaled chemotherapy and its advantages and disadvantages are presented, finding regional chemotherapy to the lung parenchyma for lung cancer is feasible and efficient.
Cerebral oximetry in cardiac anesthesia.
TLDR
Clinical validity and applicability of cerebral oximetry based on near-infrared spectroscopy for cardiac surgical patients is reviewed.
Lymphangioleiomyomatosis: current and future.
TLDR
There is no curative treatment for the disease, but the ongoing study of the genetic and molecular pathways implicated in the pathogenesis of the disease could lead to targeted therapy.
Airway inflammation in chronic obstructive pulmonary disease.
TLDR
Of particular interest for the scientific community is the discovery of clinically exploitable biomarkers associated with specific phenotypes of the disease that may lead to targeted therapy based on phenotype and this is perhaps the future of therapeutics in COPD.
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