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Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled,
BACKGROUND Fewer than half of the patients with completely resected non-small-cell lung cancer (NSCLC) are cured. Since the introduction of adjuvant chemotherapy in 2004, no substantial progress hasExpand
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Treatment of non-small cell lung cancer (NSCLC).
Radical surgery is the standard of care for fit stage I non-small cell lung cancer (NSCLC) patients. Adjuvant treatment should be offered only as part of an investigation trial. Stage II and IIIAExpand
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Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS): current literature review.
Asthma and chronic obstructive pulmonary disease (COPD) are chronic diseases, very common in general population. These obstructive airway illnesses are manifested with chronic inflammation affectingExpand
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Pneumothorax after transthoracic needle biopsy of lung lesions under CT guidance.
Transthoracic needle biopsy (TTNB) is done with imaging guidance and most frequently by a radiologist, for the aim is to diagnose a defined mass. It is integral in the diagnosis and treatment of manyExpand
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Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases
BackgroundMacrolides have long been recognised to exert immunomodulary and anti-inflammatory actions. They are able to suppress the “cytokine storm” of inflammation and to confer an additionalExpand
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Extrapelvic endometriosis: a rare entity or an under diagnosed condition?
Endometriosis is a clinical entity characterized by the presence of normal endometrial mucosa abnormally implanted in locations other than the uterine cavity. Endometriosis can be either endopelvicExpand
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Inhaled chemotherapy in lung cancer: future concept of nanomedicine
Regional chemotherapy was first used for lung cancer 30 years ago. Since then, new methods of drug delivery and pharmaceuticals have been investigated in vitro, and in animals and humans. AnExpand
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Airway inflammation in chronic obstructive pulmonary disease.
Chronic obstructive pulmonary disease (COPD) is an inflammatory airway disease whose incidence and mortality increases every year. It is associated with an abnormal inflammatory response of the lungExpand
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Cerebral oximetry in cardiac anesthesia.
Cerebral oximetry based on near-infrared spectroscopy (NIRS) is increasingly used during the perioperative period of cardiovascular operations. It is a noninvasive technology that can monitor theExpand
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Intratumoral chemotherapy for lung cancer: re-challenge current targeted therapies
Strategies to enhance the already established doublet chemotherapy regimen for lung cancer have been investigated for more than 20 years. Initially, the concept was to administer chemotherapy drugsExpand
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