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Structure of optic cup

Known as: Optic Cup 
A double walled invagination of the optical vesicles in the early embryo, which forms the neural retina from its inner wall, the retinal pigment… 
National Institutes of Health

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2 relations
Embryonic eyeOptic Disk

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Enhancement of optic cup to disc ratio detection in glaucoma diagnosis
Glaucoma is a major global cause of blindness. An approach to automatically extract the main features in color fundus images is… 
Highly Cited
2008
Highly Cited
2008
Cell autonomous roles for AP‐2α in lens vesicle separation and maintenance of the lens epithelial cell phenotype
In this study, we have created a conditional deletion of AP‐2α in the developing mouse lens (Le‐AP‐2α mutants) to determine the… 
2000
2000
Discriminant analysis models for early detection of glaucomatous optic disc changes
AIM To evaluate and compare four different mathematical formulas for the early detection of morphometric optic nerve head changes… 
Highly Cited
1997
Highly Cited
1997
Mutations affecting eye morphology in the developing zebrafish (Danio rerio).
The zebrafish (Danio rerio) has received considerable attention as a mainstream model for the molecular and genetic study of… 
Highly Cited
1990
Highly Cited
1990
Expression of the cell surface antigens RET-PE2 and N-CAM by rat retinal pigment epithelial cells during development and in tissue culture.
Highly Cited
1982
Highly Cited
1982
Variable expressivity of autosomal dominant anterior segment mesenchymal dysgenesis in six generations.
Highly Cited
1982
Highly Cited
1982
Optic cup formation: a calcium-regulated process.
Invagination of the optic vesicle to form the optic cup is an important event in the formation of the eye in the early embryo. To… 
Highly Cited
1981
Highly Cited
1981
The formation and distribution of intercellular junctions in the rhesus monkey optic cup: the early development of the cilio-iridic and sensory retinas.
1980
1980
Increased fluorescein filling defects in the wall of the optic disc cup in glaucoma.
One hundred seventy-one optic disc fluorescein angiograms of glaucomatous, ocular hypertensive, and normal patients were studied… 
Highly Cited
1967
Highly Cited
1967
The eye and skeletal effects of two mutant alleles at the microphthalmia locus of Mus musculus.
  • S. Packer
  • The Journal of experimental zoology
  • 1967
  • Corpus ID: 22586929
The mi/mi mouse has a severe microphthalmia, its skeleton shows an almost complete absence of secondary bone resorption, and its… 
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