Structure of notochord

Known as: Chordamesoderm, Notochord, Notochords 
A cartilaginous rod of mesodermal cells at the dorsal midline of all CHORDATE embryos. In lower vertebrates, notochord is the backbone of support. In… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1938-2017
05010019382016

Papers overview

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Highly Cited
1998
Highly Cited
1998
Notochord signals to the endoderm are required for development of the chick dorsal pancreas. Sonic hedgehog (SHH) is normally… (More)
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Highly Cited
1997
Highly Cited
1997
The role of the notochord in inducing and patterning adjacent neural and mesodermal tissues is well established. We provide… (More)
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Highly Cited
1996
Highly Cited
1996
Targeted gene disruption in the mouse shows that the Sonic hedgehog(Shh) gene plays a critical role in patterning of vertebrate… (More)
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Highly Cited
1996
Highly Cited
1996
THE protein Sonic hedgehog (Shh) is essential for a variety of patterning events during development. It is the signal from the… (More)
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Highly Cited
1995
Highly Cited
1995
The notochord is a midline mesodermal structure with an essential patterning function in all vertebrate embryos. Zebrafish… (More)
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Highly Cited
1995
Highly Cited
1995
The cellular interactions that control the differentiation of dorsal cell types from neural progenitors have been examined in… (More)
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Highly Cited
1994
Highly Cited
1994
HNF-3 beta, a member of the HNF-3/fork head family of transcription factors, is expressed in the node, notochord, floor plate… (More)
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Highly Cited
1993
Highly Cited
1993
We have identified three members of a mouse gene family related to the Drosophila segment polarity gene, hedgehog (hh). Like hh… (More)
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Highly Cited
1993
Highly Cited
1993
Members of the paired box (Pax) gene family are expressed in discrete regions of the developing central nervous system… (More)
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Highly Cited
1992
Highly Cited
1992
We have cloned a cDNA encoding a novel polypeptide capable of inducing dorsal development in Xenopus embryos. RNA transcripts… (More)
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