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Structure of beta Cell of islet

Known as: Type B enteroendocrine cell, Insulin-Secreting Cells, Insulin Secreting Cell 
A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.
National Institutes of Health

Related topics

Related topics

14 relations
Endocrine systemEpitheliumFree Fatty Acid Receptor 1Gastrointestinal system

Papers overview

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Highly Cited
2001
Highly Cited
2001
Transgenic rescue implicates β2-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice
Type 1 diabetes in both humans and nonobese diabetic (NOD) mice results from T-cell-mediated autoimmune destruction of insulin… 
Highly Cited
1997
Highly Cited
1997
IL-4 expression at the onset of islet inflammation predicts nondestructive insulitis in nonobese diabetic mice.
In nonobese diabetic mice, autoimmune diabetes progresses in an age-linked and gender-dependent manner. Insulitis begins in male… 
Highly Cited
1995
Highly Cited
1995
Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype.
A 4.1 kb genomic region, spanning the insulin (INS) gene, confers genetic susceptibility to Type 1 or insulin-dependent diabetes… 
Highly Cited
1993
Highly Cited
1993
Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin- dependent diabetes
Glutamic acid decarboxylase (GAD) has been shown to be a target of autoantibodies in insulin-dependent diabetes (IDD). Two forms… 
Highly Cited
1991
Highly Cited
1991
T cell receptor V gene usage of islet beta cell-reactive T cells is not restricted in non-obese diabetic mice
Five islet-reactive T cell clones were established from islet- infiltrating T cells of non-obese diabetic (NOD) mice. All clones… 
Highly Cited
1988
Highly Cited
1988
Structure of native porcine pancreatic elastase at 1.65 A resolutions.
The structure of native porcine pancreatic elastase in 70% methanol has been refined using film data to 1.65 A resolution, R = 0… 
Highly Cited
1982
Highly Cited
1982
Effect of diabetes mellitus on the regulation of enzyme secretion by isolated rat pancreatic acini.
The nature and mechanism of the pancreatic exocrine dysfunction in diabetes mellitus were evaluated in vitro using isolated… 
Highly Cited
1972
Highly Cited
1972
The stimulus-secretion coupling of glucose-induced insulin release. VII. A proposed site of action for adenosine-3',5'-cyclic monophosphate.
Glucose-induced insulin release is thought to result from the following sequence of events in the beta cell: glucose metabolism… 
Highly Cited
1971
Highly Cited
1971
Evidence for a Feedback Inhibition of Insulin on Insulin Secretion in the Isolated, Perfused Canine Pancreas
An isolated in vitro canine pancreas per fusion preparation is described which is suitable for prolonged (five hours) study of… 
Highly Cited
1947
Highly Cited
1947
The effect of hyperglycemia on insulin secretion as determined with the isolated rat pancreas in a perfusion apparatus.
VARIOUS techniques have been devised in an effort to study the factors which directly influence insulin secretion. Zunz and La… 
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