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Structure of beta Cell of islet

Known as: Type B enteroendocrine cell, Insulin-Secreting Cells, Insulin Secreting Cell 
A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.
National Institutes of Health

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Related topics

14 relations
Endocrine systemEpitheliumFree Fatty Acid Receptor 1Gastrointestinal system

Papers overview

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Highly Cited
1999
Highly Cited
1999
Evidence that beta cell death in the nonobese diabetic mouse is Fas independent.
Recent studies suggest that Fas expression on pancreatic beta cells may be important in the development of autoimmune diabetes in… 
Highly Cited
1997
Highly Cited
1997
IL-4 expression at the onset of islet inflammation predicts nondestructive insulitis in nonobese diabetic mice.
In nonobese diabetic mice, autoimmune diabetes progresses in an age-linked and gender-dependent manner. Insulitis begins in male… 
Highly Cited
1993
Highly Cited
1993
Glutamic acid decarboxylase 67-reactive T cells: a marker of insulin- dependent diabetes
Glutamic acid decarboxylase (GAD) has been shown to be a target of autoantibodies in insulin-dependent diabetes (IDD). Two forms… 
Highly Cited
1988
Highly Cited
1988
Structure of native porcine pancreatic elastase at 1.65 A resolutions.
The structure of native porcine pancreatic elastase in 70% methanol has been refined using film data to 1.65 A resolution, R = 0… 
Highly Cited
1986
Highly Cited
1986
Prevention of diabetes in BioBreeding/Worcester rats with monoclonal antibodies that recognize T lymphocytes or natural killer cells
Diabetes-prone BioBreeding/Worcester (BB/Wor) rats received thrice weekly injections of mAb against antigens expressed on the… 
Highly Cited
1978
Highly Cited
1978
Complete protection from low-dose streptozotocin-induced diabetes in mice
STREPTOZOTOCIN (SZ) is a broad-spectrum antibiotic with oncolytic, oncogenic and diabetogenic properties1–4. To produce diabetes… 
Highly Cited
1974
Highly Cited
1974
Adrenergic modulation of pancreatic glucagon secretion in man.
In order to characterize the influence of the adrenergic system on pancreatic glucagon secretion in man, changes in basal… 
Highly Cited
1973
Highly Cited
1973
Pure cholecystokinin: pancreatic protein and bicarbonate response.
In dogs with chronic pancreatic fistulas, pure cholecystokinin (CCK), CCK-variant, 20% pure CCK, octapeptide of CCK, and… 
Highly Cited
1972
Highly Cited
1972
The stimulus-secretion coupling of glucose-induced insulin release. VII. A proposed site of action for adenosine-3',5'-cyclic monophosphate.
Glucose-induced insulin release is thought to result from the following sequence of events in the beta cell: glucose metabolism… 
Highly Cited
1971
Highly Cited
1971
Evidence for a Feedback Inhibition of Insulin on Insulin Secretion in the Isolated, Perfused Canine Pancreas
An isolated in vitro canine pancreas per fusion preparation is described which is suitable for prolonged (five hours) study of… 
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