Structure of atrioventricular canal cushion

Known as: Atrioventricular Canal Cushions, Atrioventricular Canal Cushion, Endocardial Cushions 
A fetal heart structure that is the bulging areas in the cardiac septum between the HEART ATRIA and the HEART VENTRICLES. During development, growth… (More)
National Institutes of Health

Related topics

Related topics

5 relations
Common atrioventricular valveMicrobiologicalProcess of secretionaspects of radiation effects
(More)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Transitions in early embryonic atrioventricular valvular function correspond with changes in cushion biomechanics that are predictable by tissue composition.
Endocardial cushions are critical to maintain unidirectional blood flow under constantly increasing hemodynamic forces, but the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development.
Defects in cardiac valve morphogenesis and septation of the heart chambers constitute some of the most common human congenital… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation.
We have recently described a new subfamily of Fox genes, Foxp1/2/4, which are transcriptional repressors and are thought to… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo.
Endocardial cells are thought to contribute at least in part to the formation of the endocardial cushion mesenchyme. Here, we… (More)
  • figure 3
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2001
Highly Cited
2001
A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects.
Normal cardiovascular development is exquisitely dependent on the correct dosage of the angiogenic growth factor and vascular… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation, and apoptosis in TGF-beta(2)-knockout mice.
BACKGROUND Transforming growth factor-beta(2) (TGF-beta(2)) is a member of a family of growth factors with the potential to… (More)
  • table 1
  • figure 2
  • figure 1
  • figure 3
  • table 2
Is this relevant?
Review
2000
Review
2000
Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP).
Endothelial-mesenchymal transformation (EMT) is a critical event in the generation of the endocardial cushion, the primordia of… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Formation of the atrioventricular septal structures in the normal mouse.
It is sometimes thought that formation of the atrioventricular septum is equated with fusion of the endocardial cushions and that… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation.
The heart defect (hdf) mouse is a recessive lethal that arose from a transgene insertional mutation on chromosome 13. Embryos… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1.
Endothelin-1 (ET-1) is a 21-amino acid peptide with various biological activities including vasoconstriction and cell… (More)
Is this relevant?