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Streptomycin
Known as:
SM
, D-Streptamine, O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-
, 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
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An aminoglycoside antibiotic derived from Streptomyces griseus with antibacterial activity. Streptomycin irreversibly binds to the 16S rRNA and S12…
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National Institutes of Health
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Related topics
Related topics
37 relations
Aminoglycosides
Antimycobacterial agent
Antimycobacterial drug poisoning
Bacterial Endocarditis
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Broader (3)
Anti-Bacterial Agents
Antibiotics, Aminoglycoside
Antitubercular Agents
Narrower (9)
Strepto-Fatol
Strepto-Hefa
Streptomycin Sulfate
Streptotriad
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
One Juliet and four Romeos: VeA and its methyltransferases
Özlem Sarikaya-Bayram
,
J. Palmer
,
N. Keller
,
G. Braus
,
Özgür Bayram
Frontiers in Microbiology
2015
Corpus ID: 4120861
Fungal secondary metabolism has become an important research topic with great biomedical and biotechnological value. In the…
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Highly Cited
2011
Highly Cited
2011
Solution-processed small-molecule solar cells with 6.7% efficiency.
Yanming Sun
,
G. Welch
,
Wei Lin Leong
,
C. Takacs
,
G. Bazan
,
A. Heeger
Nature Materials
2011
Corpus ID: 5472348
Organic photovoltaic devices that can be fabricated by simple processing techniques are under intense investigation in academic…
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Review
2009
Review
2009
Membrane Fusion: Grappling with SNARE and SM Proteins
T. Südhof
,
J. Rothman
Science
2009
Corpus ID: 16963149
The two universally required components of the intracellular membrane fusion machinery, SNARE and SM (Sec1/Munc18-like) proteins…
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Highly Cited
2003
Highly Cited
2003
Pretreatment of Mice with Streptomycin Provides a Salmonella enterica Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host
Manja Barthel
,
S. Hapfelmeier
,
+6 authors
W. Hardt
Infection and Immunity
2003
Corpus ID: 12012762
ABSTRACT Salmonella enterica subspecies 1 serovar Typhimurium is a principal cause of human enterocolitis. For unknown reasons…
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Highly Cited
2002
Highly Cited
2002
The Diagnosis and Management of Tuberculous Meningitis
G. Thwaites
Practical Neurology
2002
Corpus ID: 73816006
INTRODUCTION The postmortem observations of Green, published in the Lancet in 1836, were the first to describe the distinct…
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Review
1995
Review
1995
Erythromycin resistance by ribosome modification
B. Weisblum
Antimicrobial Agents and Chemotherapy
1995
Corpus ID: 2951780
Erythromycin inhibits protein synthesis by its effect on ribosome function (14, 118, 119). The metabolic modifications that…
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Highly Cited
1993
Highly Cited
1993
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
Alexis Desmoulière
,
A. Geinoz
,
F. Gabbiani
,
Giulio Gabbiani
Journal of Cell Biology
1993
Corpus ID: 7582404
Granulation tissue fibroblasts (myofibroblasts) develop several ultrastructural and biochemical features of smooth muscle (SM…
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Highly Cited
1990
Highly Cited
1990
Diagnosis and treatment of disease caused by nontuberculous mycobacteria.
R. Wallace
,
R. O'Brien
,
J. Glassroth
,
J. Raleigh
,
A. Dutt
American Review of Respiratory Disease
1990
Corpus ID: 13562267
Diagnostic Criteria of Nontuberculous Mycobacterial Lung Disease For patients with a cavitary infiltrate: Two or more sputums or…
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Highly Cited
1984
Highly Cited
1984
In vitro insertional mutagenesis with a selectable DNA fragment.
P. Prentki
,
H. Krisch
Gene
1984
Corpus ID: 27651734
Highly Cited
1944
Highly Cited
1944
Streptomycin, a Substance Exhibiting Antibiotic Activity Against Gram-Positive and Gram-Negative Bacteria.∗†
A. Schatz
,
E. Bugle
,
S. Waksman
Clinical Orthopaedics and Related Research
1944
Corpus ID: 33680180
Summary A new antibacterial substance, designated as streptomycin, was isolated from two strains of an actinomyces related to an…
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