Sterol O-Acyltransferase

Known as: Cholesterol Acyltransferase, Acyltransferase, Acyl-CoA-Cholesterol, Acyl-CoA:cholesterol O-acyltransferase 
An enzyme that catalyzes the formation of cholesterol esters by the direct transfer of the fatty acid group from a fatty acyl CoA derivative. This… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2018
05010019662018

Papers overview

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Highly Cited
2009
Highly Cited
2009
Reverse cholesterol transport (RCT) is a term used to describe the efflux of excess cellular cholesterol from peripheral tissues… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The enzyme acyl-coenzyme A:cholesterol acyltransferase (ACAT) esterifies cholesterol in a variety of tissues. In some… (More)
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Highly Cited
2000
Highly Cited
2000
Triacylglycerol (TAG) is known to be synthesized in a reaction that uses acyl-CoA as acyl donor and diacylglycerol (DAG) as… (More)
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Highly Cited
1999
Highly Cited
1999
A novel and potent azetidinone inhibitor of the lipoprotein-associated phospholipase A2 (Lp-PLA2), i.e. platelet-activating… (More)
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Highly Cited
1998
Highly Cited
1998
Triacylglycerols are quantitatively the most important storage form of energy for eukaryotic cells. Acyl CoA:diacylglycerol… (More)
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Highly Cited
1998
Highly Cited
1998
The synthesis of cholesterol esters by acyl-CoA:cholesterol acyltransferase (ACAT, EC 2.3.1.26) is an important component of… (More)
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Highly Cited
1997
Highly Cited
1997
Previous studies from this laboratory have demonstrated that exposure of tissue culture cells to cyclodextrins results in rapid… (More)
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Highly Cited
1996
Highly Cited
1996
The microsomal enzyme acyl-CoA:cholesterol acyltransferase (ACAT; EC 2.3.1.26) catalyzes the esterification of cellular… (More)
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Highly Cited
1994
Highly Cited
1994
An endoplasmic reticulum-like membrane fraction, termed the "mitochondria-associated membrane" (MAM), that co-isolates with… (More)
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Highly Cited
1980
Highly Cited
1980
Mouse peritoneal macrophages take up acetylated human low density lipoprotein by receptor-mediated endocytosis, hydrolyze its… (More)
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