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Anticancer agents consisting of hybrid molecules are used to improve effectiveness and diminish drug resistance. The current… Expand Oxidative stress and inflammation have been implicated in several neurodegenerative and developmental brain disorders. The… Expand Pregnenolone (1) was used as a template to develop new anticancer compounds. Ring D modification of 1 through its reaction with… Expand Pregnenolone (1) was used as a template to develop new anticancer compounds. Ring D modification of 1 through its reaction with 4… Expand The reaction of 3beta-hydroxy-21-hydroxymethylidenepregn-5-en-3beta-ol-20-one (1) with phenylhydrazine (2a) affords two… Expand 17beta-Oxazolinyl steroids 7a-g and 8a-g were synthesized. The Lewis acid-catalysed reactions of (20R)-3beta-acetoxy-21… Expand In this study, we tested the androgenic activity of three structurally promising novel synthesized heterocyclic steroids compared… Expand During the alkaline methanolysis of 3beta-acetoxy-21-chloromethyl-pregn-5-ene-20beta-N-phenylurethane, and its p-substituted… Expand New heterocyclic analogs of estrone are reported that inhibit estradiol 17 beta-dehydrogenase (E2-17 beta DH) from human placenta… Expand A series of A-ring heterocyclic steroids has been prepared and tested for inhibition of rat prostatic steroid 5 alpha-reductase… Expand