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Statil

National Institutes of Health

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ponalrestat

Papers overview

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2010
2010
Thiol-disulfide exchanges modulate aldo-keto reductase family 1 member B10 activity and sensitivity to inhibitors.
1994
1994
Reduction of dapsone hydroxylamine to dapsone during methaemoglobin formation in human erythrocytes in vitro. III: Effect of diabetes.
Highly Cited
1993
Highly Cited
1993
Modification of the glyoxalase system in streptozotocin-induced diabetic rats. Effect of the aldose reductase inhibitor Statil.
Highly Cited
1991
Highly Cited
1991
Effect of Insulin and Statil on Aldose Reductase Expression in Diabetic Rats
Tissue accumulation of sorbitol secondary to enhanced polyol-pathway activity is believed to play an important role in the… 
Highly Cited
1990
Highly Cited
1990
Aldehyde and aldose reductases from human placenta. Heterogeneous expression of multiple enzyme forms.
1990
1990
Inhibition kinetics of human kidney aldose and aldehyde reductases by aldose reductase inhibitors.
1989
1989
Glomerular basement membrane thickening in streptozotocin diabetic rats despite treatment with an aldose reductase inhibitor.
1988
1988
Effect of Statil (ICI 128436) on Erythrocyte Viscosity In Vitro
The hypothesis that sorbitol accumulation could contribute to a reduced erythrocyte deformability in diabetes was investigated… 
Highly Cited
1986
Highly Cited
1986
Effect of hyperglycemia on sorbitol and myo-inositol content of cultured rat conceptus: failure of aldose reductase inhibitors to modify myo-inositol depletion and dysmorphogenesis.
1985
1985
Prevention of Defective Axonal Transport in Streptozocin-diabetic Rats by Treatment with “Statil” (ICI 128436), an Aldose Reductase Inhibitor
This investigation examined the effect of treatment of streptozocin-diabetic rats with the aldose reductase inhibitor “Statil… 
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