Stage IV Nasopharyngeal Carcinoma

Known as: Stage IV Nasopharynx Carcinoma AJCC v6, Nasopharyngeal Cancer, Stage IV AJCC v6, Metastatic Nasopharynx Carcinoma AJCC v6 
Stage IV nasopharyngeal cancer is divided into stages IVA, IVB, and IVC. In stage IVA, cancer has spread beyond the nasopharynx and may have spread… (More)
National Institutes of Health

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Chromosome 13q deletionEpithelial CellsEpitheliumHLA-A gene
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Papers overview

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Highly Cited
2009
Highly Cited
2009
Identification of novel Epstein-Barr virus microRNA genes from nasopharyngeal carcinomas.
MicroRNAs (miRNAs) represent a conserved class of small noncoding RNAs that are found in all higher eukaryotes as well as some… (More)
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Highly Cited
2008
Highly Cited
2008
The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis.
Streptococcus salivarius is an early colonizer of human oral and nasopharyngeal epithelia, and strain K12 has reported probiotic… (More)
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Review
2007
Review
2007
Nasopharyngeal carcinoma: molecular pathogenesis and therapeutic developments.
Nasopharyngeal carcinoma (NPC) is a prevalent tumour in southern China and southeast Asia, particularly in the Cantonese… (More)
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Highly Cited
2007
Highly Cited
2007
Biofilms formed by nontypeable Haemophilus influenzae in vivo contain both double-stranded DNA and type IV pilin protein.
Nontypeable Haemophilus influenzae (NTHI) strains are members of the normal human nasopharyngeal flora, as well as frequent… (More)
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Highly Cited
2006
Highly Cited
2006
Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral Latent Membrane Protein 1 and the immunomodulatory protein galectin 9
Nasopharyngeal carcinomas (NPC) are consistently associated with the Epstein-Barr virus (EBV). Their malignant epithelial cells… (More)
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Highly Cited
2005
Highly Cited
2005
Cell therapy of stage IV nasopharyngeal carcinoma with autologous Epstein-Barr virus-targeted cytotoxic T lymphocytes.
PURPOSE Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-related malignancy expressing EBV antigens that are… (More)
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Review
2004
Review
2004
EBV-associated nasopharyngeal carcinomas: from epidemiology to virus-targeting strategies.
Nasopharyngeal carcinoma is a human malignancy consistently associated with the Epstein-Barr virus. Exposure to non-viral… (More)
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Highly Cited
2001
Highly Cited
2001
Intranasal vaccination with pneumococcal surface protein A and interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection.
Streptococcus pneumoniae is a major pathogen in humans that enters the host primarily through the respiratory tract. Targeting… (More)
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Highly Cited
2000
Highly Cited
2000
Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae.
Acquisition of pneumococci is generally from carriers rather than from infected individuals. Therefore, to induce herd immunity… (More)
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Highly Cited
1992
Highly Cited
1992
Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcripts.
Epstein-Barr virus (EBV) genome-positive nasopharyngeal carcinomas (NPCs) regularly express the virus-coded nuclear antigen EBNA1… (More)
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