Squalene monooxygenase

Known as: Squalene Monooxygenase (2,3-Epoxidizing), Squalene Epoxidase, Epoxidase, Squalene 
The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of… (More)
National Institutes of Health

Papers overview

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2014
2014
In recent years, there has been an increased interest in the research and development of sustainable alternatives to fossil fuels… (More)
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2013
2013
Sterol homeostasis is essential for the function of cellular membranes and requires feedback inhibition of HMGR, a rate-limiting… (More)
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2011
2011
Exquisite control of cholesterol synthesis is crucial for maintaining homeostasis of this vital yet potentially toxic lipid… (More)
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Review
2009
Review
2009
Hypercholesterolemia is a major risk factor for the development of atherosclerotic vascular diseases. The most popular agents for… (More)
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2002
2002
Selenosis in animals is characterized by a variety of neurological abnormalities, but the chemical species of selenium and the… (More)
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2001
2001
Squalene monooxygenase is a flavin adenine dinucleotide-containing, microsomal enzyme that catalyzes the second step in the… (More)
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2000
2000
The cDNA for human squalene monooxygenase, a key enzyme in the committed pathway for cholesterol biosynthesis, was amplified from… (More)
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2000
2000
Pneumocystis carinii synthesizes sterols with a double bond at C-7 of the sterol nucleus and an alkyl group with one or two… (More)
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Review
1992
Review
1992
Terbinafine (Lamisil) has primarily fungicidal action against many fungi as a result of its specific mechanism of squalene… (More)
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1991
1991
We have reported previously that NB-598 competitively inhibits human squalene epoxidase and strongly inhibits cholesterol… (More)
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