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Splicing Factor U2AF

Known as: Factor, U2AF Splicing, U2AF 65, Splicing Factor, U2AF 
An RNA splicing factor that performs a critical function in both constitutive and enhancer-dependent RNA SPLICING. It recruits RIBONUCLEOPROTEIN, U2… 
National Institutes of Health

Related topics

Related topics

11 relations
In BloodProcess of secretionagonistsantagonists & inhibitors

Narrower (3)

MUD2 protein, S cerevisiaeU2AF2 protein, humanU2af1l4 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Large favorable enthalpy changes drive specific RNA recognition by RNA recognition motif proteins.
The RNA recognition motif (RRM) is a prevalent class of RNA binding domains. Although a number of RRM/RNA structures have been… 
2011
2011
Genetic basis of sex determination in the haplodiploid wasp Nasonia vitripennis
In all examined insects thus far, sex is determined by a cascade of genes with doublesex (dsx) at the bottom of the cascade and… 
2010
2010
Mechanisms and Functional Roles of Pseudouridines in RNAs
Pre-mRNA splicing is an essential RNA processing reaction by which intervening sequences (introns) are removed and protein-coding… 
2008
2008
Backbone assignment of the UHM domain of Puf60 free and bound to five ligands
U2AF homology motifs (UHM) are protein domains that bind peptidic UHM ligand motifs (ULM) and thus form an intricate network of… 
2007
2007
Factors associated with a purine-rich exonic splicing enhancer sequence in Xenopus oocyte nucleus.
2005
2005
Mutations in the small subunit of the Drosophila U 2 AF splicing factor cause lethality and developmental defects ( fruit fly / pre-mRNA splicing / RNA-binding proteins / RS domains )
The essential eukaryotic pre-mRNA splicing factor U2AF (U2 small nuclear ribonucleoprotein auxiliary factor) is required to… 
2004
2004
Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo.
The heterodimeric splicing factor U2AF plays an important role in 3' splice site selection, but the division of labor between the… 
2003
2003
An early ancestor in the evolution of splicing: a Trypanosoma cruzi serine-arginine-rich protein (TcSR) is functional in cis-splicing.
2002
2002
Characterization of U2AF(6), a splicing factor related to U2AF(35).
The essential splicing factor U2AF (U2 auxiliary factor) is a heterodimer composed of 65-kDa (U2AF(65)) and 35-kDa (U2AF(35… 
Highly Cited
1998
Highly Cited
1998
Interaction between Subunits of Heterodimeric Splicing Factor U2AF Is Essential In Vivo
ABSTRACT The heterodimeric pre-mRNA splicing factor, U2AF (U2 snRNP auxiliary factor), plays a critical role in 3′ splice site… 
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