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Splicing Factor U2AF
Known as:
Factor, U2AF Splicing
, U2AF 65
, Splicing Factor, U2AF
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An RNA splicing factor that performs a critical function in both constitutive and enhancer-dependent RNA SPLICING. It recruits RIBONUCLEOPROTEIN, U2…
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National Institutes of Health
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Related topics
Related topics
11 relations
In Blood
Process of secretion
agonists
antagonists & inhibitors
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Narrower (3)
MUD2 protein, S cerevisiae
U2AF2 protein, human
U2af1l4 protein, mouse
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
An interaction between U2AF 65 and CF Im links the splicing and 3′ end processing machineries
S. Millevoi
,
Clarisse Loulergue
,
+4 authors
S. Vagner
EMBO Journal
2006
Corpus ID: 12414523
The protein factor U2 snRNP Auxiliary Factor (U2AF) 65 is an essential component required for splicing and involved in the…
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Highly Cited
2006
Highly Cited
2006
Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65.
E. Sickmier
,
Katherine E Frato
,
Hai-hong Shen
,
S. Paranawithana
,
Michael R. Green
,
C. Kielkopf
Molecules and Cells
2006
Corpus ID: 1796826
Highly Cited
2004
Highly Cited
2004
A pathway of sequential arginine-serine-rich domain-splicing signal interactions during mammalian spliceosome assembly.
Hai-hong Shen
,
Michael R. Green
Molecules and Cells
2004
Corpus ID: 33657357
Highly Cited
2003
Highly Cited
2003
Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP.
Philipp Selenko
,
G. Gregorovic
,
+4 authors
M. Sattler
Molecules and Cells
2003
Corpus ID: 34226795
Highly Cited
2001
Highly Cited
2001
The role of U2AF35 and U2AF65 in enhancer-dependent splicing.
B. Graveley
,
K. Hertel
,
Tom Maniatis
RNA: A publication of the RNA Society
2001
Corpus ID: 21722571
Splicing enhancers are RNA sequence elements that promote the splicing of nearby introns. The mechanism by which these elements…
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Highly Cited
2000
Highly Cited
2000
The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing.
Stéphan Vagner
,
Christine Vagner
,
I. Mattaj
Genes & Development
2000
Corpus ID: 23597572
Although it has been established that the processing factors involved in pre-mRNA splicing and 3'-end formation can influence…
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Highly Cited
1998
Highly Cited
1998
Interaction between Subunits of Heterodimeric Splicing Factor U2AF Is Essential In Vivo
D. Rudner
,
R. Kanaar
,
K. S. Breger
,
D. Rio
Molecular and Cellular Biology
1998
Corpus ID: 37283421
ABSTRACT The heterodimeric pre-mRNA splicing factor, U2AF (U2 snRNP auxiliary factor), plays a critical role in 3′ splice site…
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Highly Cited
1996
Highly Cited
1996
The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.
P. Zuo
,
T. Maniatis
Genes & Development
1996
Corpus ID: 46665177
The splicing factor U2AF (U2 snRNP auxiliary factor) is a heterodimer with subunits of 65 and 35 kD (U2AF65 and U2AF35). U2AF65…
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Highly Cited
1996
Highly Cited
1996
The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex.
H. Colot
,
F. Stutz
,
M. Rosbash
Genes & Development
1996
Corpus ID: 45834389
The mechanism by which pre-mRNAs are initially recognized by the splicing machinery is not well understood. In the yeast system…
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Highly Cited
1993
Highly Cited
1993
The conserved pre-mRNA splicing factor U2AF from Drosophila: requirement for viability.
R. Kanaar
,
S. Roche
,
E. Beall
,
M. Green
,
D. Rio
Science
1993
Corpus ID: 19702517
The large subunit of the human pre-messenger RNA splicing factor U2 small nuclear ribonucleoprotein auxiliary factor (hU2AF65) is…
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