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Splicing Factor U2AF

Known as: Factor, U2AF Splicing, U2AF 65, Splicing Factor, U2AF 
An RNA splicing factor that performs a critical function in both constitutive and enhancer-dependent RNA SPLICING. It recruits RIBONUCLEOPROTEIN, U2… 
National Institutes of Health

Related topics

Related topics

11 relations
In BloodProcess of secretionagonistsantagonists & inhibitors

Narrower (3)

MUD2 protein, S cerevisiaeU2AF2 protein, humanU2af1l4 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Large favorable enthalpy changes drive specific RNA recognition by RNA recognition motif proteins.
The RNA recognition motif (RRM) is a prevalent class of RNA binding domains. Although a number of RRM/RNA structures have been… 
2009
2009
Interactome for auxiliary splicing factor U2AF(65) suggests diverse roles.
2008
2008
The transcription factor c-Myb affects pre-mRNA splicing.
Review
2006
Review
2006
Diversity of human U2AF splicing factors
U2 snRNP auxiliary factor (U2AF) is an essential heterodimeric splicing factor composed of two subunits, U2AF65 and U2AF35… 
2004
2004
Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo.
The heterodimeric splicing factor U2AF plays an important role in 3' splice site selection, but the division of labor between the… 
2003
2003
U2 small nuclear ribonucleoprotein particle (snRNP) auxiliary factor of 65 kDa, U2AF65, can promote U1 snRNP recruitment to 5' splice sites.
The splicing factor U2AF(65), U2 small nuclear ribonucleoprotein particle (snRNP) auxillary factor of 65 kDa, binds to pyrimidine… 
2003
2003
An early ancestor in the evolution of splicing: a Trypanosoma cruzi serine-arginine-rich protein (TcSR) is functional in cis-splicing.
2002
2002
Characterization of U2AF(6), a splicing factor related to U2AF(35).
The essential splicing factor U2AF (U2 auxiliary factor) is a heterodimer composed of 65-kDa (U2AF(65)) and 35-kDa (U2AF(35… 
2001
2001
Reorganization of nuclear factors during myeloid differentiation
Differentiation in several stem cell systems is associated with major morphological changes in global nuclear shape. We studied… 
Highly Cited
1998
Highly Cited
1998
Interaction between Subunits of Heterodimeric Splicing Factor U2AF Is Essential In Vivo
ABSTRACT The heterodimeric pre-mRNA splicing factor, U2AF (U2 snRNP auxiliary factor), plays a critical role in 3′ splice site… 
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