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Splicing Factor U2AF

Known as: Factor, U2AF Splicing, U2AF 65, Splicing Factor, U2AF 
An RNA splicing factor that performs a critical function in both constitutive and enhancer-dependent RNA SPLICING. It recruits RIBONUCLEOPROTEIN, U2… 
National Institutes of Health

Related topics

Related topics

11 relations
In BloodProcess of secretionagonistsantagonists & inhibitors

Narrower (3)

MUD2 protein, S cerevisiaeU2AF2 protein, humanU2af1l4 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
An interaction between U2AF 65 and CF Im links the splicing and 3′ end processing machineries
The protein factor U2 snRNP Auxiliary Factor (U2AF) 65 is an essential component required for splicing and involved in the… 
Highly Cited
2005
Highly Cited
2005
Polypyrimidine tract binding protein blocks the 5' splice site-dependent assembly of U2AF and the prespliceosomal E complex.
Highly Cited
2004
Highly Cited
2004
A pathway of sequential arginine-serine-rich domain-splicing signal interactions during mammalian spliceosome assembly.
Highly Cited
2003
Highly Cited
2003
Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP.
Highly Cited
2001
Highly Cited
2001
The role of U2AF35 and U2AF65 in enhancer-dependent splicing.
Splicing enhancers are RNA sequence elements that promote the splicing of nearby introns. The mechanism by which these elements… 
Highly Cited
1999
Highly Cited
1999
Both subunits of U2AF recognize the 3′ splice site in Caenorhabditis elegans
Introns are defined by sequences that bind components of the splicing machinery. The branchpoint consensus, polypyrimidine (poly… 
Highly Cited
1998
Highly Cited
1998
A Potential Role for U2AF-SAP 155 Interactions in Recruiting U2 snRNP to the Branch Site
ABSTRACT Base pairing between U2 snRNA and the branchpoint sequence (BPS) is essential for pre-mRNA splicing. Because the… 
Highly Cited
1996
Highly Cited
1996
The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.
The splicing factor U2AF (U2 snRNP auxiliary factor) is a heterodimer with subunits of 65 and 35 kD (U2AF65 and U2AF35). U2AF65… 
Highly Cited
1993
Highly Cited
1993
The conserved pre-mRNA splicing factor U2AF from Drosophila: requirement for viability.
The large subunit of the human pre-messenger RNA splicing factor U2 small nuclear ribonucleoprotein auxiliary factor (hU2AF65) is… 
Highly Cited
1992
Highly Cited
1992
Cloning and domain structure of the mammalian splicing factor U2AF
A complementary DNA clone encoding the large subunit of the essential mammalian premessenger RNA splicing component U2 snRNP… 
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