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Spleen Development

Human Spleen Development involves formation of the spleen, initially as a long strip of cells adjacent to the forming stomach, from mesoderm in the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Secondary lymphoid organ stromal cells comprise different subsets whose origins remain unknown. Herein, we exploit a genetic… Expand
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Highly Cited
2013
Highly Cited
2013
Spleen Knockout Explained Isolated congenital asplenia (ICA) is a rare disorder where patients are born without a spleen and are… Expand
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2009
2009
As part of our recent study on mitochondria injury and increased apoptosis in lymphocyte spleen cells of young chickens fed high… Expand
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Highly Cited
2007
Highly Cited
2007
Homeobox genes convey positional information in embryos and their role in patterning the mammalian gut is a topic of considerable… Expand
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Highly Cited
2005
Highly Cited
2005
The genetic control of cell fate specification, morphogenesis and expansion of the spleen, a crucial lymphoid organ, is poorly… Expand
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2001
2001
The genetic steps governing development of the spleen are largely unknown. Absence of Hox11 in mice results in asplenia, but it… Expand
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2000
2000
Mice deficient in Hox11 are asplenic. As Hoxll can function as a transcription factor, we examined the spatial and temporal mRNA… Expand
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Highly Cited
1999
Highly Cited
1999
The Wilms tumor suppressor gene WT1 (wt1 in mouse) is unique among tumor suppressors because, in addition to its involvement in… Expand
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1998
1998
Hox11 is a homeobox gene essential for spleen formation in mice, since atrophy of the anlage of a developing spleen occurs in… Expand
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Highly Cited
1995
Highly Cited
1995
The HOX11 homeobox gene was identified via the translocation t(10;14) in T cell leukaemia. To determine the function of this gene… Expand
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