Spleen Development

Human Spleen Development involves formation of the spleen, initially as a long strip of cells adjacent to the forming stomach, from mesoderm in the… (More)

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Topic mentions per year

1970-2018
02419702018

Papers overview

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2013
2013
Secondary lymphoid organ stromal cells comprise different subsets whose origins remain unknown. Herein, we exploit a genetic… (More)
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2013
2013
Isolated congenital asplenia (ICA) is characterized by the absence of a spleen at birth in individuals with no other… (More)
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2009
2009
In this report we describe a transplantation system where embryonic spleens are grafted into adult hosts. This model can be used… (More)
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2007
2007
Homeobox genes convey positional information in embryos and their role in patterning the mammalian gut is a topic of considerable… (More)
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2005
2005
The genetic control of cell fate specification, morphogenesis and expansion of the spleen, a crucial lymphoid organ, is poorly… (More)
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2001
2001
The genetic steps governing development of the spleen are largely unknown. Absence of Hox11 in mice results in asplenia, but it… (More)
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2000
2000
Mice deficient in Hox11 are asplenic. As Hoxll can function as a transcription factor, we examined the spatial and temporal mRNA… (More)
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Highly Cited
1999
Highly Cited
1999
The Wilms tumor suppressor gene WT1 (wt1 in mouse) is unique among tumor suppressors because, in addition to its involvement in… (More)
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1998
1998
Hox11 is a homeobox gene essential for spleen formation in mice, since atrophy of the anlage of a developing spleen occurs in… (More)
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1995
1995
The HOX11 homeobox gene was identified via the translocation t(10;14) in T cell leukaemia. To determine the function of this gene… (More)
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