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Spacer Oligonucleotide Typing

A PCR-based method for differentiating M. tuberculosis strains based on amplification of the polymorphic direct repeat locus.
National Institutes of Health

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Review
2012
Review
2012
Background Tuberculosis (TB), caused by Mycobacterium tuberculosis complex (MTBC), is one of the major causes of death in the… Expand
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2009
2009
BackgroundBovine tuberculosis (BTB), caused by Mycobacterium bovis, has remained a major source of concern to public health… Expand
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Highly Cited
2006
Highly Cited
2006
We present a novel approach for analysis of Mycobacterium tuberculosis complex (MTC) strain genotyping data. Our work presents a… Expand
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Highly Cited
2002
Highly Cited
2002
MOTIVATION The Direct Repeat (DR) locus of Mycobacterium tuberculosis is a suitable model to study (i) molecular epidemiology and… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT A total of 204 isoniazid (INH)-resistant strains of Mycobacterium tuberculosis isolated from different patients in the… Expand
Highly Cited
2001
Highly Cited
2001
Spacer oligonucleotide typing (spoligotyping) is widely used for differentiation of bacteria of the Mycobacterium tuberculosis… Expand
Highly Cited
1999
Highly Cited
1999
We used direct repeat (DR)-based spacer oligonucleotide typing (spoligotyping) (in association with double-repetitive element… Expand
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Highly Cited
1999
Highly Cited
1999
ABSTRACT Restriction fragment length polymorphism (RFLP) analysis with probes derived from the insertion element IS6110, the… Expand
Highly Cited
1998
Highly Cited
1998
The combination of conventional investigation and DNA fingerprinting is yielding important insights into the epidemiology of… Expand
Highly Cited
1996
Highly Cited
1996
The spacer oligonucleotide typing (spoligotyping) method was evaluated for its ability to differentiate Mycobacterium bovis… Expand