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Spacer Oligonucleotide Typing

A PCR-based method for differentiating M. tuberculosis strains based on amplification of the polymorphic direct repeat locus.
National Institutes of Health

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2009
2009
BackgroundBovine tuberculosis (BTB), caused by Mycobacterium bovis, has remained a major source of concern to public health… Expand
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2007
2007
A large diphtheria epidemic in the 1990s in Russia and neighboring countries underlined the importance of permanent surveillance… Expand
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Highly Cited
2006
Highly Cited
2006
We present a novel approach for analysis of Mycobacterium tuberculosis complex (MTC) strain genotyping data. Our work presents a… Expand
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Highly Cited
2002
Highly Cited
2002
MOTIVATION The Direct Repeat (DR) locus of Mycobacterium tuberculosis is a suitable model to study (i) molecular epidemiology and… Expand
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Highly Cited
2002
Highly Cited
2002
A total of 204 isoniazid (INH)-resistant strains of Mycobacterium tuberculosis isolated from different patients in the… Expand
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Highly Cited
2001
Highly Cited
2001
Spacer oligonucleotide typing (spoligotyping) is widely used for differentiation of bacteria of the Mycobacterium tuberculosis… Expand
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1999
1999
We used direct repeat (DR)-based spacer oligonucleotide typing (spoligotyping) (in association with double-repetitive element… Expand
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Highly Cited
1999
Highly Cited
1999
Restriction fragment length polymorphism (RFLP) analysis with probes derived from the insertion element IS6110, the direct repeat… Expand
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1998
1998
The combination of conventional investigation and DNA fingerprinting is yielding important insights into the epidemiology of… Expand
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Highly Cited
1996
Highly Cited
1996
The spacer oligonucleotide typing (spoligotyping) method was evaluated for its ability to differentiate Mycobacterium bovis… Expand
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