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Spacer Oligonucleotide Typing

A PCR-based method for differentiating M. tuberculosis strains based on amplification of the polymorphic direct repeat locus.
National Institutes of Health

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2013
2009
2009
BackgroundBovine tuberculosis (BTB), caused by Mycobacterium bovis, has remained a major source of concern to public health… 
Highly Cited
2002
Highly Cited
2002
MOTIVATION The Direct Repeat (DR) locus of Mycobacterium tuberculosis is a suitable model to study (i) molecular epidemiology and… 
Highly Cited
2002
Highly Cited
2002
ABSTRACT A total of 204 isoniazid (INH)-resistant strains of Mycobacterium tuberculosis isolated from different patients in the… 
Highly Cited
2001
Highly Cited
2001
Spacer oligonucleotide typing (spoligotyping) is widely used for differentiation of bacteria of the Mycobacterium tuberculosis… 
Highly Cited
1999
Highly Cited
1999
We used direct repeat (DR)-based spacer oligonucleotide typing (spoligotyping) (in association with double-repetitive element… 
Highly Cited
1999
Highly Cited
1999
ABSTRACT Restriction fragment length polymorphism (RFLP) analysis with probes derived from the insertion element IS6110, the… 
Highly Cited
1996
Highly Cited
1996
The spacer oligonucleotide typing (spoligotyping) method was evaluated for its ability to differentiate Mycobacterium bovis…