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Spacer Oligonucleotide Typing

A PCR-based method for differentiating M. tuberculosis strains based on amplification of the polymorphic direct repeat locus.
National Institutes of Health

Papers overview

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2017
2017
Genetic diversity of the Mycobacterium tuberculosis East African-Indian family in three tropical Asian countries.
Review
2016
Review
2016
Molecular Strain Typing of Mycobacterium tuberculosis: a Review of Frequently Used Methods
Tuberculosis, caused by the bacterium Mycobacterium tuberculosis, remains one of the most serious global health problems… 
Review
2012
Review
2012
Spoligotyping and Drug Resistance Analysis of Mycobacterium tuberculosis Strains from National Survey in China
Background Tuberculosis (TB), caused by Mycobacterium tuberculosis complex (MTBC), is one of the major causes of death in the… 
2009
2009
Isolation and characterization of Mycobacterium bovis strains from indigenous Zambian cattle using Spacer oligonucleotide typing technique
BackgroundBovine tuberculosis (BTB), caused by Mycobacterium bovis, has remained a major source of concern to public health… 
2008
2008
Spoligotypes of Mycobacterium tuberculosis isolates of a high tuberculosis burden aboriginal township in Taiwan.
Highly Cited
2007
Highly Cited
2007
Corynebacterium diphtheriae spoligotyping based on combined use of two CRISPR loci
A large diphtheria epidemic in the 1990s in Russia and neighboring countries underlined the importance of permanent surveillance… 
2007
2007
Laboratory Investigation of a Nosocomial Transmission of Tuberculosis at a District General Hospital
Highly Cited
2002
Highly Cited
2002
A data-mining approach to spacer oligonucleotide typing of Mycobacterium tuberculosis
MOTIVATION The Direct Repeat (DR) locus of Mycobacterium tuberculosis is a suitable model to study (i) molecular epidemiology and… 
Highly Cited
2001
Highly Cited
2001
Genetic Diversity of Mycobacterium africanum Clinical Isolates Based on IS6110-Restriction Fragment Length Polymorphism Analysis, Spoligotyping, and Variable Number of Tandem DNA Repeats
ABSTRACT A collection of 105 clinical isolates originally identified asMycobacterium africanum were characterized using both… 
Highly Cited
1998
Highly Cited
1998
Restriction fragment length polymorphism and spacer oligonucleotide typing: a comparative analysis of fingerprinting strategies for Mycobacterium bovis.
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