FAQ

Solute Carrier Family 12, Member 1

Known as: Protein, SLC12A1, SLC12A1 Cotransporter, BSC1 Transport Protein 
Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption of sodium chloride and is inhibited by LOOP DIURETICS… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2016
01219972016

Related topics

Related topics

13 relations
Bartter DiseaseIn BloodProcess of secretionSLC12A1 gene
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Narrower (2)

Bartter syndrome, antenatal type 1SLC12A1 protein, human

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Solute Carrier Family 12, Member 1
physiological aspects
In Blood
chemical synthesis
Bartter Disease
sodium-potassium-chloride cotransporter 1 protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Furosemide loading test in a case of homozygous solute carrier family 12, member 1 (SLC12A1) mutation (g.62382825G>A, p.Pro372Leu) in Japanese Black cattle.
Hydrallantois is the excessive accumulation of fluid in the allantoic cavity in a pregnant animal and is associated with fetal… (More)
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2016
2016
A missense mutation in solute carrier family 12, member 1 (SLC12A1) causes hydrallantois in Japanese Black cattle
Hydrallantois is the excessive accumulation of fluid within the allantoic cavity in pregnant animals and is associated with fetal… (More)
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2014
2014
Disruption of the ATE1 and SLC12A1 Genes by Balanced Translocation in a Boy with Non-Syndromic Hearing Loss.
We report on a boy with non-syndromic hearing loss and an apparently balanced translocation t(10;15)(q26.13;q21.1). The same… (More)
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2013
2013
Adenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCC.
Arginine vasopressin (AVP) affects kidney function via vasopressin V2 receptors that are linked to activation of adenylyl cyclase… (More)
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2011
2011
Gene expression profiling in ethnic Malays with type 2 diabetes mellitus, with and without diabetic nephropathy.
BACKGROUND Diabetic nephropathy (DN) is the most common cause of end-stage renal disease (ESRD) among type 2 diabetes mellitus… (More)
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2009
2009
A highly conserved motif at the COOH terminus dictates endoplasmic reticulum exit and cell surface expression of NKCC2.
Mutations in the apically located Na(+)-K(+)-2Cl(-) co-transporter, NKCC2, lead to type I Bartter syndrome, a life-threatening… (More)
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2007
2007
NKCC2 surface expression in mammalian cells: down-regulation by novel interaction with aldolase B.
Apical bumetanide-sensitive Na(+)-K(+)-2Cl(-) co-transporter, termed NKCC2, is the major salt transport pathway in kidney thick… (More)
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2006
2006
Neurogenic mechanisms contribute to hypertension in mice with disruption of the K-Cl cotransporter KCC3.
The neurodegenerative disorder Andermann syndrome is caused by mutations of the K-Cl cotransporter KCC3. Mice with a targeted… (More)
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Review
2001
Review
2001
Serum- and glucocorticoid-dependent kinase, cell volume, and the regulation of epithelial transport.
Ample pharmacological evidence points to a role of kinases in the regulation of cell volume. Given the limited selectivity of… (More)
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1997
1997
Mutations in the gene encoding the inwardly-rectifying renal potassium channel, ROMK, cause the antenatal variant of Bartter syndrome: evidence for genetic heterogeneity. International Collaborative…
  • Human molecular genetics
  • 1997
Inherited renal tubular disorders associated with hypokalemic alkalosis (Bartter-like syndromes) can be subdivided into at least… (More)
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