Small Inducible Cytokine A18

Known as: PARC chemokine, human, Thymus and Activation-Regulated Chemokine, small inducible cytokine subfamily A, member 18 protein, human 
C-C motif chemokine 18 (89 aa, ~10 kDa) is encoded by the human CCL18 gene. This protein is involved in both B-cell migration and T-lymphocyte… (More)
National Institutes of Health

Related topics

Related topics

21 relations
Biologic DevelopmentCCL17 geneCCL17 protein, humanCCL18 gene
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Broader (2)

beta-Chemokineschemokine

Papers overview

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Highly Cited
2014
Highly Cited
2014
A positive feedback loop between mesenchymal-like cancer cells and macrophages is essential to breast cancer metastasis.
The close vicinity of cancer cells undergoing epithelial-mesenchymal transition (EMT) and tumor-associated macrophages (TAMs) at… (More)
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Highly Cited
2013
Highly Cited
2013
Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages.
Multipotent stromal cells (MSC) have been shown to possess immunomodulatory capacities and are therefore explored as a novel… (More)
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Highly Cited
2011
Highly Cited
2011
CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3.
Tumor-associated macrophages (TAMs) can influence cancer progression and metastasis, but the mechanism remains unclear. Here, we… (More)
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Highly Cited
2009
Highly Cited
2009
Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis.
RATIONALE Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with a poor prognosis. There is great effort to find… (More)
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Highly Cited
2006
Highly Cited
2006
A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18.
RATIONALE Recently, models of macrophage activation have been revised. Macrophages stimulated with Th2 cytokines have been… (More)
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Highly Cited
2004
Highly Cited
2004
Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention.
Gaucher disease is characterized by storage of glucosylceramide in lysosomes of tissue macrophages as the result of an autosomal… (More)
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Highly Cited
2002
Highly Cited
2002
Identification of biologically active chemokine isoforms from ascitic fluid and elevated levels of CCL18/pulmonary and activation-regulated chemokine in ovarian carcinoma.
Chemokines are important in leukocyte homeostasis, inflammation, angiogenesis, and metastasis. Here, the molecular diversity of… (More)
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2000
2000
C-C chemokine receptor 3 antagonism by the beta-chemokine macrophage inflammatory protein 4, a property strongly enhanced by an amino-terminal alanine-methionine swap.
Allergic reactions are characterized by the infiltration of tissues by activated eosinophils, Th2 lymphocytes, and basophils. The… (More)
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1999
1999
Media Spaces: Environments for Informal Multimedia Interaction
Distributed organizations, with distributed cooperative work, are a fact of life. How can new technologies help? Distributed… (More)
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Highly Cited
1996
Highly Cited
1996
The Parctab Ubiquitous Computing Experiment
The PARCTAB system integrates a palm-sized mobile computer into an office network. This project serves as a preliminary testbed… (More)
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